PDB entry 1exx

View 1exx on RCSB PDB site
Description: enantiomer discrimination illustrated by crystal structures of the human retinoic acid receptor hrargamma ligand binding domain: the complex with the inactive s-enantiomer bms270395.
Class: gene regulation
Keywords: enantiomer discrimination, retinoid ligand complexes, antiparallel alpha-helical sandwich fold, Structural Proteomics in Europe, SPINE, Structural Genomics, GENE REGULATION
Deposited on 2000-05-05, released 2000-06-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-24, with a file datestamp of 2019-07-19.
Experiment type: XRAY
Resolution: 1.67 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: retinoic acid receptor gamma-2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1exxa_
  • Heterogens: 961, LMU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1exxA (A:)
dsyelspqleelitkvskahqetfpslcqlgkyttnssadhrvqldlglwdkfselatkc
iikivefakrlpgftglsiadqitllkaacldilmlrictrytpeqdtmtfsdgltlnrt
qmhnagfgpltdlvfafagqllplemddtetgllsaiclicgdrmdleepekvdklqepl
lealrlyarrrrpsqpymfprmlmkitdlrgistkgaeraitlkmeipgpmppliremle
npemfe

    Sequence, based on observed residues (ATOM records): (download) 
    >1exxA (A:)
lspqleelitkvskahqetfpslcqlgkyttnssadhrvqldlglwdkfselatkciiki
vefakrlpgftglsiadqitllkaacldilmlrictrytpeqdtmtfsdgltlnrtqmhn
agfgpltdlvfafagqllplemddtetgllsaiclicgdrmdleepekvdklqeplleal
rlyarrrrpsqpymfprmlmkitdlrgistkgaeraitlkmeipgpmppliremle