PDB entry 1ex8
View 1ex8 on RCSB PDB site
Description: crystal structure of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase complexed with hp4a, the two-substrate-mimicking inhibitor
Class: transferase
Keywords: pyrophosphokinase, pyrophosphoryl transfer, folate, hppk, pterin, ATP, bisubstrate-mimicking inhibitor, antimicrobial agent, drug design, substrate specificity, active-site architecture, x-ray crystallography, transferase
Deposited on
2000-05-01, released
2001-05-01
The last revision prior to the SCOPe 2.08 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.211
AEROSPACI score: 0.44
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase
Species: Escherichia coli [TaxId:562]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1ex8a_ - Heterogens: MG, CL, A4P, HOH