PDB entry 1ewq

View 1ewq on RCSB PDB site
Description: crystal structure taq muts complexed with a heteroduplex DNA at 2.2 a resolution
Class: replication/DNA
Keywords: Multiple domains of protein, mostly mixed alpha-beta structures, one domain is entirely helical, double stranded helix, replication-DNA COMPLEX
Deposited on 2000-04-26, released 2000-10-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-04, with a file datestamp of 2017-09-29.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA mismatch repair protein muts
    Species: Thermus aquaticus [TaxId:271]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q56215
      • engineered (0)
      • engineered (3)
      • engineered (69)
      • engineered (87)
      • engineered (200)
      • engineered (249)
      • engineered (480)
      • engineered (573)
      • engineered (585)
      • engineered (639)
      • engineered (642)
      • engineered (743)
      • engineered (761)
    Domains in SCOPe 2.08: d1ewqa1, d1ewqa2, d1ewqa3, d1ewqa4
  • Chain 'B':
    Compound: DNA mismatch repair protein muts
    Species: Thermus aquaticus [TaxId:271]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q56215 (0-End)
      • engineered (0)
      • engineered (3)
      • engineered (69)
      • engineered (87)
      • engineered (200)
      • engineered (249)
      • engineered (480)
      • engineered (573)
      • engineered (585)
      • engineered (639)
      • engineered (642)
      • engineered (743)
      • engineered (761)
    Domains in SCOPe 2.08: d1ewqb1, d1ewqb2, d1ewqb3, d1ewqb4
  • Chain 'C':
    Compound: DNA (5'-d(*gp*cp*gp*ap*cp*gp*cp*tp*ap*gp*cp*gp*tp*gp*cp*gp*gp*cp*tp*cp*gp*tp*c)-3')
  • Chain 'D':
    Compound: DNA (5'-d(*gp*gp*ap*cp*gp*ap*gp*cp*cp*gp*cp*cp*gp*cp*tp*ap*gp*cp*gp*tp*cp*g)-3')
  • Heterogens: SO4, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ewqA (A:)
megmlkgegpgplppllqqyvelrdqypdylllfqvgdfyecfgedaerlaralglvlth
ktskdfttpmagiplrafeayaerllkmgfrlavadqvepaeeaeglvrrevtqlltpgt
llqesllpreanylaaiatgdgwglafldvstgefkgtvlksksalydelfrhrpaevll
apellengafldefrkrfpvmlseapfepegegplalrrargallayaqrtqggalslqp
frfydpgafmrlpeatlralevfeplrgqdtlfsvldetrtapgrrllqswlrhplldrg
plearldrvegfvregalregvrrllyrladlerlatrlelgraspkdlgalrrslqilp
elrallgeevglpdlsplkeeleaalvedpplkvseggliregydpdldalraahregva
yfleleererertgiptlkvgynavfgyylevtrpyyervpkeyrpvqtlkdrqrytlpe
mkekerevyrlealirrreeevflevrerakrqaealreaarilaeldvyaalaevavry
gyvrprfgdrlqiragrhpvverrtefvpndlemahelvlitgpnmagkstflrqtalia
llaqvgsfvpaeeahlplfdgiytrigasddlaggkstfmvemeevalilkeatenslvl
ldevgrgtssldgvaiatavaealherraytlfathyfeltalglprlknlhvaareeag
glvfyhqvlpgpasksygvevaamaglpkevvararallqamaar

    Sequence, based on observed residues (ATOM records): (download) 
    >1ewqA (A:)
megmlkgegpgplppllqqyvelrdqypdylllfqvgdfyecfgedaerlaralglvlth
ktskdfttpmagiplrafeayaerllkmgfrlavadqvepaeeaeglvrrevtqlltpgt
llqesllpreanylaaiatgdgwglafldvstgefkgtvlksksalydelfrhrpaevll
apellengafldefrkrfpvmlseapfepegegplalrrargallayaqrtqggalslqp
frfydpgafmrlpeatlralevfeplrgqdtlfsvldetrtapgrrllqswlrhplldrg
plearldrvegfvregalregvrrllyrladlerlatrlelgraspkdlgalrrslqilp
elrallgeevglpdlsplkeeleaalvedpplkvseggliregydpdldalraahregva
yfleleererertgiptlkvgynavfgyylevtrpyyervpkeyrpvqtlkdrqrytlpe
mkekerevyrlealirrreeevflevrerakrqaealreaarilaeldvyaalaevavry
gyvrprfgdrlqiragrhpvverrtefvpndlemahelvlitgpnmagkstflrqtalia
llaqvgsfvpaeeahlplfdgiytrigagkstfmvemeevalilkeatenslvlldevgr
gtssldgvaiatavaealherraytlfathyfeltalglprlknlhvaareeagglvfyh
qvlpgpasksygvevaamaglpkevvararallqamaar

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1ewqB (B:)
megmlkgegpgplppllqqyvelrdqypdylllfqvgdfyecfgedaerlaralglvlth
ktskdfttpmagiplrafeayaerllkmgfrlavadqvepaeeaeglvrrevtqlltpgt
llqesllpreanylaaiatgdgwglafldvstgefkgtvlksksalydelfrhrpaevll
apellengafldefrkrfpvmlseapfepegegplalrrargallayaqrtqggalslqp
frfydpgafmrlpeatlralevfeplrgqdtlfsvldetrtapgrrllqswlrhplldrg
plearldrvegfvregalregvrrllyrladlerlatrlelgraspkdlgalrrslqilp
elrallgeevglpdlsplkeeleaalvedpplkvseggliregydpdldalraahregva
yfleleererertgiptlkvgynavfgyylevtrpyyervpkeyrpvqtlkdrqrytlpe
mkekerevyrlealirrreeevflevrerakrqaealreaarilaeldvyaalaevavry
gyvrprfgdrlqiragrhpvverrtefvpndlemahelvlitgpnmagkstflrqtalia
llaqvgsfvpaeeahlplfdgiytrigasddlaggkstfmvemeevalilkeatenslvl
ldevgrgtssldgvaiatavaealherraytlfathyfeltalglprlknlhvaareeag
glvfyhqvlpgpasksygvevaamaglpkevvararallqamaar

    Sequence, based on observed residues (ATOM records): (download) 
    >1ewqB (B:)
megmlkgegpgplppllqqyvelrdqypdylllfqvgdfyecfgedaerlaralglvlth
ktskdfttpmagiplrafeayaerllkmgfrlavadqvepvrrevtqlltpgtllqesll
preanylaaiatgdgwglafldvstgefkgtvlksksalydelfrhrpaevllapellen
gafldefrkrfpvmlseapfepegegplalrrargallayaqrtqggalslqpfrfydpg
afmrlpeatlralevfeplrgqdtlfsvldetrtapgrrllqswlrhplldrgplearld
rvegfvregalregvrrllyrladlerlatrlelgraspkdlgalrrslqilpelrallg
eevglpdlsplkeeleaalvedpplkvseggliregydpdldalraahregvayflelee
rerertgiptlkvgynavfgyylevtrpyyervpkeyrpvqtlkdrqrytlpemkekere
vyrlealirrreeevflevrerakrqaealreaarilaeldvyaalaevavrygyvrprf
gdrlqiragrhpvverrtefvpndlemahelvlitgpnmagkstflrqtaliallaqvgs
fvpaeeahlplfdgiytrigagkstfmvemeevalilkeatenslvlldevgrgtssldg
vaiatavaealherraytlfathyfeltalglprlknlhvaareeagglvfyhqvlpgpa
sksygvevaamaglpkevvararallqam

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.