PDB entry 1ewp

View 1ewp on RCSB PDB site
Description: cruzain bound to mor-leu-hpq
Class: HYDROLASE/HYDROLASE inhibitor
Keywords: cysteine protease, drug design, covalent inhibitor, cruzipain, HYDROLASE, HYDROLASE-HYDROLASE inhibitor complex
Deposited on 2000-04-26, released 2000-05-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.183
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: cruzain
  Species: Trypanosoma cruzi [TaxId:5693]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P25779 (0-214)
  Domains in SCOPe 2.08: d1ewpa_
• Heterogens: 0I5, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1ewpA (A:)
  apaavdwrargavtavkdqgqcgscwafsaignvecqwflaghpltnlseqmlvscdktd
  sgcsgglmnnafewivqenngavytedsypyasgegisppcttsghtvgatitghvelpq
  deaqiaawlavngpvavavdasswmtytggvmtscvseqldhgvllvgyndsaavpywii
  knswttqwgeegyiriakgsnqclvkeeassavvg