PDB entry 1ewn

View 1ewn on RCSB PDB site
Description: crystal structure of the human aag DNA repair glycosylase complexed with 1,n6-ethenoadenine-DNA
Class: hydrolase/DNA
Keywords: DNA repair, glycosylase, AAG, ANPG, MPG, 3-methyladenine DNA glycosylase, hydrolase/DNA COMPLEX
Deposited on 2000-04-26, released 2000-12-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.23
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-methyl-adenine DNA glycosylase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P29372
      • engineered (45)
    Domains in SCOPe 2.07: d1ewna_
  • Chain 'D':
    Compound: DNA (5'-d(*gp*ap*cp*ap*tp*gp*(eda)p*tp*tp*gp*cp*c)-3')
  • Chain 'E':
    Compound: DNA (5'-d(p*gp*cp*ap*ap*tp*cp*ap*tp*gp*tp*cp*a)-3')
  • Heterogens: NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ewnA (A:)
kghltrlgleffdqpavplaraflgqvlvrrlpngtelrgrivetqaylgpedeaahsrg
grqtprnrgmfmkpgtlyvyiiygmyfcmnissqgdgacvllraleplegletmrqlrst
lrkgtasrvlkdrelcsgpsklcqalainksfdqrdlaqdeavwlergplepsepavvaa
arvgvghagewarkplrfyvrgspwvsvvdrvaeqdtqa

    Sequence, based on observed residues (ATOM records): (download) 
    >1ewnA (A:)
hltrlgleffdqpavplaraflgqvlvrrlpngtelrgrivetqaylgpedeaahsrggr
qtprnrgmfmkpgtlyvyiiygmyfcmnissqgdgacvllraleplegletmrqlrstvl
kdrelcsgpsklcqalainksfdqrdlaqdeavwlergpavvaaarvgvghagewarkpl
rfyvrgspwvsvvdrvaeqd

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.