PDB entry 1esv

View 1esv on RCSB PDB site
Description: complex between latrunculin a:rabbit muscle alpha actin:human gelsolin domain 1
Class: contractile protein
Keywords: Latrunculin A, Gelsolin, Actin, Depolymerisation, Sequestration, CONTRACTILE PROTEIN
Deposited on 2000-04-11, released 2000-07-19
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.228
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: alpha actin
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P68135 (Start-376)
      • modified residue (74)
    Domains in SCOPe 2.07: d1esva1, d1esva2
  • Chain 'S':
    Compound: gelsolin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06396 (0-124)
      • engineered (32)
    Domains in SCOPe 2.07: d1esvs_
  • Heterogens: CA, ATP, LAR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1esvA (A:)
    mcdedettalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdea
    qskrgiltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrek
    mtqimfetfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrl
    dlagrdltdylmkiltergysfvttaereivrdikeklcyvaldfenemataasssslek
    syelpdgqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannv
    msggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwit
    kqeydeagpsivhrkcf
    

    Sequence, based on observed residues (ATOM records): (download)
    >1esvA (A:)
    talvcdngsglvkagfagddapravfpsivgrprdsyvgdeaqskrgiltlkypiehgii
    tnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimfetfnvpamyvai
    qavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrdltdylmkilter
    gysfvttaereivrdikeklcyvaldfenemataassssleksyelpdgqvitignerfr
    cpetlfqpsfigmesagihettynsimkcdidirkdlyannvmsggttmypgiadrmqke
    italapstmkikiiapperkysvwiggsilaslstfqqmwitkqeydeagpsivhrkcf
    

  • Chain 'S':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1esvS (S:)
    mvvehpeflkagkepglqiwrvekfdlvpvptclygdfftgdayvilktvqlrngnlqyd
    lhywlgnecsqdesgaaaiftvqlddylngravqhrevqgfesatflgyfksglkykkgg
    vasgf