PDB entry 1es7

View 1es7 on RCSB PDB site
Description: complex between bmp-2 and two bmp receptor ia ectodomains
Class: cytokine
Keywords: protein-protein complex, three finger toxin fold, receptor-ligand complex, cytokine receptor, TGF beta superfamily
Deposited on 2000-04-07, released 2000-10-07
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.191
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: bone morphogenetic protein-2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1es7a_
  • Chain 'B':
    Compound: bone morphogenetic protein receptor ia
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1es7b_
  • Chain 'C':
    Compound: bone morphogenetic protein-2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1es7c_
  • Chain 'D':
    Compound: bone morphogenetic protein receptor ia
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1es7d_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1es7A (A:)
maqakhkqrkrlkssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnst
nhaivqtlvnsvnskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr

    Sequence, based on observed residues (ATOM records): (download) 
    >1es7A (A:)
kssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnhaivqtlvnsv
nskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1es7B (B:)
tlpflkcycsghcpddainntcitnghcfaiieeddqgettlasgcmkyegsdfqckdsp
kaqlrrtieccrtnlcnqylqptlppvvi

    Sequence, based on observed residues (ATOM records): (download) 
    >1es7B (B:)
tlpflkcycsghcpddainntcitnghcfaiieedettlasgcmkyegsdfqckdspkaq
lrrtieccrtnlcnqylqptlpp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1es7C (C:)
maqakhkqrkrlkssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnst
nhaivqtlvnsvnskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr

    Sequence, based on observed residues (ATOM records): (download) 
    >1es7C (C:)
kssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnhaivqtlvnsv
nskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1es7D (D:)
tlpflkcycsghcpddainntcitnghcfaiieeddqgettlasgcmkyegsdfqckdsp
kaqlrrtieccrtnlcnqylqptlppvvi

    Sequence, based on observed residues (ATOM records): (download) 
    >1es7D (D:)
tlpflkcycsghcpddainntcitnghcfaiieedettlasgcmkyegsdfqckdspkaq
lrrtieccrtnlcnqylqptlppvvi