PDB entry 1egd

View 1egd on RCSB PDB site
Description: structure of t255e, e376g mutant of human medium chain acyl-coa dehydrogenase
Class: electron transfer
Keywords: acyl-coa dehydrogenase, flavoprotein, electron transfer
Deposited on 1996-04-11, released 1997-06-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.208
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: medium chain acyl-coa dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11310 (Start-395)
      • engineered (254)
      • engineered (375)
    Domains in SCOPe 2.08: d1egda1, d1egda2
  • Chain 'B':
    Compound: medium chain acyl-coa dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11310 (Start-395)
      • engineered (254)
      • engineered (375)
    Domains in SCOPe 2.08: d1egdb1, d1egdb2
  • Chain 'C':
    Compound: medium chain acyl-coa dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11310 (Start-395)
      • engineered (254)
      • engineered (375)
    Domains in SCOPe 2.08: d1egdc1, d1egdc2
  • Chain 'D':
    Compound: medium chain acyl-coa dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11310 (Start-395)
      • engineered (254)
      • engineered (375)
    Domains in SCOPe 2.08: d1egdd1, d1egdd2
  • Heterogens: FAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1egdA (A:)
kanrqrepglgfsfefteqqkefqatarkfareeiipvaaeydktgeypvplirrawelg
lmnthipencgglglgtfdacliseelaygctgvqtaiegnslgqmpiiiagndqqkkky
lgrmteeplmcaycvtepgagsdvagiktkaekkgdeyiingqkmwitnggkanwyflla
rsdpdpkapankaftgfiveadtpgiqigrkelnmgqrcsdtrgivfedvkvpkenvlig
dgagfkvamgafdkerpvvaagavglaqraldeatkyalerktfgkllvehqaisfmlae
mamkvelarmsyqraawevdsgrrntyyasiakafagdianqlatdavqilggngfntey
pveklmrdakiyqiyggtsqiqrlivarehidkykn

    Sequence, based on observed residues (ATOM records): (download) 
    >1egdA (A:)
lgfsfefteqqkefqatarkfareeiipvaaeydktgeypvplirrawelglmnthipen
cgglglgtfdacliseelaygctgvqtaiegnslgqmpiiiagndqqkkkylgrmteepl
mcaycvtepgagsdvagiktkaekkgdeyiingqkmwitnggkanwyfllarsdpdpkap
ankaftgfiveadtpgiqigrkelnmgqrcsdtrgivfedvkvpkenvligdgagfkvam
gafdkerpvvaagavglaqraldeatkyalerktfgkllvehqaisfmlaemamkvelar
msyqraawevdsgrrntyyasiakafagdianqlatdavqilggngfnteypveklmrda
kiyqiyggtsqiqrlivarehidkykn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1egdB (B:)
kanrqrepglgfsfefteqqkefqatarkfareeiipvaaeydktgeypvplirrawelg
lmnthipencgglglgtfdacliseelaygctgvqtaiegnslgqmpiiiagndqqkkky
lgrmteeplmcaycvtepgagsdvagiktkaekkgdeyiingqkmwitnggkanwyflla
rsdpdpkapankaftgfiveadtpgiqigrkelnmgqrcsdtrgivfedvkvpkenvlig
dgagfkvamgafdkerpvvaagavglaqraldeatkyalerktfgkllvehqaisfmlae
mamkvelarmsyqraawevdsgrrntyyasiakafagdianqlatdavqilggngfntey
pveklmrdakiyqiyggtsqiqrlivarehidkykn

    Sequence, based on observed residues (ATOM records): (download) 
    >1egdB (B:)
lgfsfefteqqkefqatarkfareeiipvaaeydktgeypvplirrawelglmnthipen
cgglglgtfdacliseelaygctgvqtaiegnslgqmpiiiagndqqkkkylgrmteepl
mcaycvtepgagsdvagiktkaekkgdeyiingqkmwitnggkanwyfllarsdpdpkap
ankaftgfiveadtpgiqigrkelnmgqrcsdtrgivfedvkvpkenvligdgagfkvam
gafdkerpvvaagavglaqraldeatkyalerktfgkllvehqaisfmlaemamkvelar
msyqraawevdsgrrntyyasiakafagdianqlatdavqilggngfnteypveklmrda
kiyqiyggtsqiqrlivarehidkykn

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1egdC (C:)
kanrqrepglgfsfefteqqkefqatarkfareeiipvaaeydktgeypvplirrawelg
lmnthipencgglglgtfdacliseelaygctgvqtaiegnslgqmpiiiagndqqkkky
lgrmteeplmcaycvtepgagsdvagiktkaekkgdeyiingqkmwitnggkanwyflla
rsdpdpkapankaftgfiveadtpgiqigrkelnmgqrcsdtrgivfedvkvpkenvlig
dgagfkvamgafdkerpvvaagavglaqraldeatkyalerktfgkllvehqaisfmlae
mamkvelarmsyqraawevdsgrrntyyasiakafagdianqlatdavqilggngfntey
pveklmrdakiyqiyggtsqiqrlivarehidkykn

    Sequence, based on observed residues (ATOM records): (download) 
    >1egdC (C:)
lgfsfefteqqkefqatarkfareeiipvaaeydktgeypvplirrawelglmnthipen
cgglglgtfdacliseelaygctgvqtaiegnslgqmpiiiagndqqkkkylgrmteepl
mcaycvtepgagsdvagiktkaekkgdeyiingqkmwitnggkanwyfllarsdpdpkap
ankaftgfiveadtpgiqigrkelnmgqrcsdtrgivfedvkvpkenvligdgagfkvam
gafdkerpvvaagavglaqraldeatkyalerktfgkllvehqaisfmlaemamkvelar
msyqraawevdsgrrntyyasiakafagdianqlatdavqilggngfnteypveklmrda
kiyqiyggtsqiqrlivarehidkykn

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1egdD (D:)
kanrqrepglgfsfefteqqkefqatarkfareeiipvaaeydktgeypvplirrawelg
lmnthipencgglglgtfdacliseelaygctgvqtaiegnslgqmpiiiagndqqkkky
lgrmteeplmcaycvtepgagsdvagiktkaekkgdeyiingqkmwitnggkanwyflla
rsdpdpkapankaftgfiveadtpgiqigrkelnmgqrcsdtrgivfedvkvpkenvlig
dgagfkvamgafdkerpvvaagavglaqraldeatkyalerktfgkllvehqaisfmlae
mamkvelarmsyqraawevdsgrrntyyasiakafagdianqlatdavqilggngfntey
pveklmrdakiyqiyggtsqiqrlivarehidkykn

    Sequence, based on observed residues (ATOM records): (download) 
    >1egdD (D:)
lgfsfefteqqkefqatarkfareeiipvaaeydktgeypvplirrawelglmnthipen
cgglglgtfdacliseelaygctgvqtaiegnslgqmpiiiagndqqkkkylgrmteepl
mcaycvtepgagsdvagiktkaekkgdeyiingqkmwitnggkanwyfllarsdpdpkap
ankaftgfiveadtpgiqigrkelnmgqrcsdtrgivfedvkvpkenvligdgagfkvam
gafdkerpvvaagavglaqraldeatkyalerktfgkllvehqaisfmlaemamkvelar
msyqraawevdsgrrntyyasiakafagdianqlatdavqilggngfnteypveklmrda
kiyqiyggtsqiqrlivarehidkykn