PDB entry 1efx

View 1efx on RCSB PDB site
Description: structure of a complex between the human natural killer cell receptor kir2dl2 and a class I MHC ligand hla-cw3
Class: immune system
Keywords: MHC, HLA, class I, KIR, NK cell receptor, Immunoglobulin fold, receptor/MHC complex
Deposited on 2000-02-10, released 2000-06-14
The last revision prior to the SCOP 1.73 freeze date was dated 2003-09-30, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.231
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla-cw3 (heavy chain)
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • GB AAA88088 (0-277)
    Domains in SCOP 1.73: d1efxa1, d1efxa2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • see remark 999 (0)
    Domains in SCOP 1.73: d1efxb_
  • Chain 'C':
    Compound: peptide from importin alpha-2
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: natural killer cell receptor kir2dl2
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1efxd1, d1efxd2
  • Chain 'E':
    Compound: natural killer cell receptor kir2dl2
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1efxe1, d1efxe2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1efxA (A:)
    gshsmryfytavsrpgrgephfiavgyvddtqfvrfdsdaasprgeprapwveqegpeyw
    dretqkykrqaqtdrvslrnlrgyynqseagshiiqrmygcdvgpdgrllrgydqyaydg
    kdyialnedlrswtaadtaaqitqrkweaareaeqlrayleglcvewlrrylkngketlq
    raehpkthvthhpvsdheatlrcwalgfypaeitltwqwdgedqtqdtelvetrpagdgt
    fqkwaavvvpsgeeqrytchvqheglpepltlrwepss
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1efxB (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1efxD (D:)
    hegvhrkpsllahpgrlvkseetvilqcwsdvrfehfllhregkfkdtlhligehhdgvs
    kanfsigpmmqdlagtyrcygsvthspyqlsapsdpldivitglyekpslsaqpgptvla
    gesvtlscssrssydmyhlsregeahecrfsagpkvngtfqadfplgpathggtyrcfgs
    frdspyewsnssdpllvsvi
    

    Sequence, based on observed residues (ATOM records): (download)
    >1efxD (D:)
    vhrkpsllahpgrlvkseetvilqcwsdvrfehfllhregkfkdtlhligehhdgvskan
    fsigpmmqdlagtyrcygsvthspyqlsapsdpldivitglyekpslsaqpgptvlages
    vtlscssrssydmyhlsregeahecrfsagpkvngtfqadfplgpathggtyrcfgsfrd
    spyewsnssdpllvsvi
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >1efxE (E:)
    hegvhrkpsllahpgrlvkseetvilqcwsdvrfehfllhregkfkdtlhligehhdgvs
    kanfsigpmmqdlagtyrcygsvthspyqlsapsdpldivitglyekpslsaqpgptvla
    gesvtlscssrssydmyhlsregeahecrfsagpkvngtfqadfplgpathggtyrcfgs
    frdspyewsnssdpllvsvi
    

    Sequence, based on observed residues (ATOM records): (download)
    >1efxE (E:)
    vhrkpsllahpgrlvkseetvilqcwsdvrfehfllhregkfkdtlhligehhdgvskan
    fsigpmmqdlagtyrcygsvthspyqlsapsdpldivitglyekpslsaqpgptvlages
    vtlscssrssydmyhlsregeahecrfsagpkvngtfqadfplgpathggtyrcfgsfrd
    spyewsnssdpllvsvi