PDB entry 1efa

View 1efa on RCSB PDB site
Description: crystal structure of the lac repressor dimer bound to operator and the anti-inducer onpf
Class: transcription/DNA
Keywords: protein-dna complex, helix-turn-helix, gene regulation, molecular switch, TRANSCRIPTION-DNA COMPLEX
Deposited on 2000-02-07, released 2000-03-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: lac repressor
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03023
      • engineered (108)
    Domains in SCOPe 2.08: d1efaa1, d1efaa2
  • Chain 'B':
    Compound: lac repressor
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03023
      • engineered (108)
    Domains in SCOPe 2.08: d1efab1, d1efab2
  • Chain 'C':
    Compound: lac repressor
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03023
      • engineered (108)
    Domains in SCOPe 2.08: d1efac1, d1efac2
  • Chain 'D':
    Compound: DNA (5'-d(*gp*ap*ap*t*tp*gp*tp*gp*ap*gp*cp*gp*cp*tp*cp*ap*cp*ap*ap*tp*t)-3')
  • Chain 'E':
    Compound: DNA (5'-d(*gp*ap*ap*t*tp*gp*tp*gp*ap*gp*cp*gp*cp*tp*cp*ap*cp*ap*ap*tp*t)-3')
  • Heterogens: NPF, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1efaA (A:)
mkpvtlydvaeyagvsyqtvsrvvnqashvsaktrekveaamaelnyipnrvaqqlagkq
slligvatsslalhapsqivaaiksradqlgasvvvsmversgveacktavhnllaqrvs
gliinyplddqdaiaveaactnvpalfldvsdqtpinsiifshedgtrlgvehlvalghq
qiallagplssvsarlrlagwhkyltrnqiqpiaeregdwsamsgfqqtmqmlnegivpt
amlvandqmalgamraitesglrvgadisvvgyddtedsscyipplttikqdfrllgqts
vdrllqlsqgqavkgnqllpvslvkrkttlapn

    Sequence, based on observed residues (ATOM records): (download) 
    >1efaA (A:)
kpvtlydvaeyagvsyqtvsrvvnqashvsaktrekveaamaelnyipnrvaqqlagkqs
lligvatsslalhapsqivaaiksradqlgasvvvsmversgveacktavhnllaqrvsg
liinyplddqdaiaveaactnvpalfldvsdqtpinsiifshedgtrlgvehlvalghqq
iallagplssvsarlrlagwhkyltrnqiqpiaeregdwsamsgfqqtmqmlnegivpta
mlvandqmalgamraitesglrvgadisvvgyddtedsscyipplttikqdfrllgqtsv
drllqlsqgqavkgnqllpvslvkrktt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1efaB (B:)
mkpvtlydvaeyagvsyqtvsrvvnqashvsaktrekveaamaelnyipnrvaqqlagkq
slligvatsslalhapsqivaaiksradqlgasvvvsmversgveacktavhnllaqrvs
gliinyplddqdaiaveaactnvpalfldvsdqtpinsiifshedgtrlgvehlvalghq
qiallagplssvsarlrlagwhkyltrnqiqpiaeregdwsamsgfqqtmqmlnegivpt
amlvandqmalgamraitesglrvgadisvvgyddtedsscyipplttikqdfrllgqts
vdrllqlsqgqavkgnqllpvslvkrkttlapn

    Sequence, based on observed residues (ATOM records): (download) 
    >1efaB (B:)
kpvtlydvaeyagvsyqtvsrvvnqashvsaktrekveaamaelnyipnrvaqqlagkqs
lligvatsslalhapsqivaaiksradqlgasvvvsmversgveacktavhnllaqrvsg
liinyplddqdaiaveaactnvpalfldvsdqtpinsiifshedgtrlgvehlvalghqq
iallagplssvsarlrlagwhkyltrnqiqpiaeregdwsamsgfqqtmqmlnegivpta
mlvandqmalgamraitesglrvgadisvvgyddtedsscyipplttikqdfrllgqtsv
drllqlsqgqavkgnqllpvslvkrkttla

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1efaC (C:)
mkpvtlydvaeyagvsyqtvsrvvnqashvsaktrekveaamaelnyipnrvaqqlagkq
slligvatsslalhapsqivaaiksradqlgasvvvsmversgveacktavhnllaqrvs
gliinyplddqdaiaveaactnvpalfldvsdqtpinsiifshedgtrlgvehlvalghq
qiallagplssvsarlrlagwhkyltrnqiqpiaeregdwsamsgfqqtmqmlnegivpt
amlvandqmalgamraitesglrvgadisvvgyddtedsscyipplttikqdfrllgqts
vdrllqlsqgqavkgnqllpvslvkrkttlapn

    Sequence, based on observed residues (ATOM records): (download) 
    >1efaC (C:)
nyipnrvaqqlagkqslligvatsslalhapsqivaaiksradqlgasvvvsmversgve
acktavhnllaqrvsgliinyplddqdaiaveaactnvpalfldvsdqtpinsiifshed
gtrlgvehlvalghqqiallagplssvsarlrlagwhkyltrnqiqpiaeregdwsamsg
fqqtmqmlnegivptamlvandqmalgamraitesglrvgadisvvgyddtedsscyipp
lttikqdfrllgqtsvdrllqlsqgqavkgnqllpvslvkrkttla

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.