PDB entry 1ecl

View 1ecl on RCSB PDB site
Description: amino terminal 67kda domain of escherichia coli DNA topoisomerase I (residues 2-590 of mature protein) cloning artifact adds two residues to the amino-terminus which were not observed in the experimental electron density (gly-2, ser-1).
Class: topoisomerase
Keywords: bacterial type I, DNA cleavage, strand passage, topoisomerase
Deposited on 1995-05-05, released 1995-07-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-04-04, with a file datestamp of 2018-03-29.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: escherichia coli topoisomerase I
    Species: Escherichia coli [TaxId:562]
    Gene: TOPA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1ecla_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1eclA (A:)
mgkalvivespakaktinkylgsdyvvkssvghirdlptsgsaakksadststktakkpk
kdergalvnrmgvdpwhnweahyevlpgkekvvselkqlaekadhiylatdldregeaia
whlreviggddarysrvvfneitknairqafnkpgelnidrvnaqqarrfmdrvvgymvs
pllwkkiarglsagrvqsvavrlvverereikafvpeefwevdastttpsgealalqvth
qndkpfrpvnkeqtqaavsllekarysvleredkpttskpgapfitstlqqaastrlgfg
vkktmmmaqrlyeagyitymrtdstnlsqdavnmvrgyisdnfgkkylpespnqyaskgn
sqeaheairpsdvnvmaeslkdmeadaqklyqliwrqfvacqmtpakydsttltvgagdf
rlkargrilrfdgwtkvmpalrkgdedrilpavnkgdaltlveltpaqhftkpparfsea
slvkelekrgigrpstyasiistiqdrgyvrvenrrfyaekmgeivtdrleenfrelmny
dftaqmensldqvanheaewkavldhffsdftqqldkaekdpeeggmrpnqmvltsi

    Sequence, based on observed residues (ATOM records): (download) 
    >1eclA (A:)
gkalvivespakaktinkylgsdyvvkssvghirdlpdergalvnrmgvdpwhnweahye
vlpgkekvvselkqlaekadhiylatdldregeaiawhlreviggddarysrvvfneitk
nairqafnkpgelnidrvnaqqarrfmdrvvgymvspllwkkiarglsagrvqsvavrlv
verereikafvpeefwevdastttpsgealalqvthqndkpfrpvnkeqtqaavslleka
rysvleredkpttskpgapfitstlqqaastrlgfgvkktmmmaqrlyeagyitymrtds
tnlsqdavnmvrgyisdnfgkkylpespnqyaheairpsdvnvmaeslkdmeadaqklyq
liwrqfvacqmtpakydsttltvgagdfrlkargrilrfdgwtkvmpalrilpavnkgda
ltlveltpaqhftkpparfseaslvkelekrgigrpstyasiistiqdrgyvrvenrrfy
aekmgeivtdrleenfrelmnydftaqmensldqvanheaewkavldhffsdftqqldka
ekdpeeggmrpn