PDB entry 1eaw

View 1eaw on RCSB PDB site
Description: crystal structure of the mtsp1 (matriptase)-bpti (aprotinin) complex
Class: hydrolase/inhibitor
Keywords: hydrolase/inhibitor, complex (serine protease inhibitor), serine proteinase, matrix degradation, inhibitor, glycoprote hydrolase
Deposited on 2001-07-17, released 2002-01-28
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.93 Å
R-factor: 0.199
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: suppressor of tumorigenicity 14
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1eawa_
  • Chain 'B':
    Compound: pancreatic trypsin inhibitor
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1eawb_
  • Chain 'C':
    Compound: suppressor of tumorigenicity 14
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1eawc_
  • Chain 'D':
    Compound: pancreatic trypsin inhibitor
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1eawd_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1eawA (A:)
    vvggtdadegewpwqvslhalgqghicgaslispnwlvsaahcyiddrgfrysdptqwta
    flglhdqsqrsapgvqerrlkriishpffndftfdydiallelekpaeyssmvrpiclpd
    ashvfpagkaiwvtgwghtqyggtgalilqkgeirvinqttcenllpqqitprmmcvgfl
    sggvdscqgdsggplssveadgrifqagvvswgdgcaqrnkpgvytrlplfrdwikentg
    v
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1eawB (B:)
    rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga
    

    Sequence, based on observed residues (ATOM records): (download)
    >1eawB (B:)
    rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcg
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1eawC (C:)
    vvggtdadegewpwqvslhalgqghicgaslispnwlvsaahcyiddrgfrysdptqwta
    flglhdqsqrsapgvqerrlkriishpffndftfdydiallelekpaeyssmvrpiclpd
    ashvfpagkaiwvtgwghtqyggtgalilqkgeirvinqttcenllpqqitprmmcvgfl
    sggvdscqgdsggplssveadgrifqagvvswgdgcaqrnkpgvytrlplfrdwikentg
    v
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1eawD (D:)
    rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga
    

    Sequence, based on observed residues (ATOM records): (download)
    >1eawD (D:)
    rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcg