PDB entry 1eaw
View 1eaw on RCSB PDB site
Description: Crystal structure of the MTSP1 (matriptase)-BPTI (aprotinin) complex
Class: hydrolase/inhibitor
Keywords: HYDROLASE/INHIBITOR, COMPLEX (SERINE PROTEASE INHIBITOR), SERINE PROTEINASE, MATRIX DEGRADATION, INHIBITOR, GLYCOPROTE HYDROLASE, HYDROLASE-INHIBITOR complex
Deposited on
2001-07-17, released
2002-01-28
The last revision prior to the SCOPe 2.08 freeze date was dated
2015-04-01, with a file datestamp of
2015-03-27.
Experiment type: XRAY
Resolution: 2.93 Å
R-factor: N/A
AEROSPACI score: 0.14
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: suppressor of tumorigenicity 14
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1eawa_ - Chain 'B':
Compound: pancreatic trypsin inhibitor
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1eawb_ - Chain 'C':
Compound: suppressor of tumorigenicity 14
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1eawc_ - Chain 'D':
Compound: pancreatic trypsin inhibitor
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1eawd_ - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1eawA (A:)
vvggtdadegewpwqvslhalgqghicgaslispnwlvsaahcyiddrgfrysdptqwta
flglhdqsqrsapgvqerrlkriishpffndftfdydiallelekpaeyssmvrpiclpd
ashvfpagkaiwvtgwghtqyggtgalilqkgeirvinqttcenllpqqitprmmcvgfl
sggvdscqgdsggplssveadgrifqagvvswgdgcaqrnkpgvytrlplfrdwikentg
v
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1eawB (B:)
rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga
Sequence, based on observed residues (ATOM records): (download)
>1eawB (B:)
rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcg
- Chain 'C':
Sequence; same for both SEQRES and ATOM records: (download)
>1eawC (C:)
vvggtdadegewpwqvslhalgqghicgaslispnwlvsaahcyiddrgfrysdptqwta
flglhdqsqrsapgvqerrlkriishpffndftfdydiallelekpaeyssmvrpiclpd
ashvfpagkaiwvtgwghtqyggtgalilqkgeirvinqttcenllpqqitprmmcvgfl
sggvdscqgdsggplssveadgrifqagvvswgdgcaqrnkpgvytrlplfrdwikentg
v
- Chain 'D':
Sequence, based on SEQRES records: (download)
>1eawD (D:)
rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga
Sequence, based on observed residues (ATOM records): (download)
>1eawD (D:)
rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcg