PDB entry 1eat

View 1eat on RCSB PDB site
Description: nonpeptidic inhibitors of human leukocyte elastase. 5. design, synthesis, and x-ray crystallography of a series of orally active 5-amino-pyrimidin-6-one-containing trifluoromethylketones
Class: hydrolase (serine protease)
Keywords: hydrolase (serine protease)
Deposited on 1994-11-22, released 1995-02-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-02-22, with a file datestamp of 2012-02-17.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.167
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: porcine pancreatic elastase
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00772 (0-239)
      • conflict (65)
    Domains in SCOPe 2.08: d1eata_
  • Heterogens: NA, SO4, TFI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1eatA (A:)