PDB entry 1e9c

View 1e9c on RCSB PDB site
Description: mutant human thymidylate kinase complexed with tmp and appnp
Class: phosphotransferase
Keywords: phosphotransferase, thymidylate kinase, p-loop
Deposited on 2000-10-10, released 2001-10-11
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.209
AEROSPACI score: 0.58 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: thymidylate kinase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1E9C
      • engineered mutation (202)
      • conflict (185)
      • conflict (192)
      • conflict (186)
      • conflict (193)
      • conflict (107)
      • conflict (210)
    • Uniprot P23919 (Start-214)
    Domains in SCOPe 2.02: d1e9ca_
  • Heterogens: TMP, ADP, ANP, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1e9cA (A:)
gshmaarrgalivlegvdragkstqsrklvealcaaghraellrfpersteigkllssyl
qkksdvedhsvhllfsanrweqvplikeklsqgvtlvvdryafsgvaytgakenfsldwc
kqpdvglpkpdlvlflqlqladaakrgafgheryengafqeralrcfhqlmkdttlnwkm
vdasksieavhedirvlsedaiatatekplkelwk

    Sequence, based on observed residues (ATOM records): (download) 
    >1e9cA (A:)
rrgalivlegvdragkstqsrklvealcaaghraellrfpersteigkllssylqkksdv
edhsvhllfsanrweqvplikeklsqgvtlvvdryafsgvaytgakenfsldwckqpdvg
lpkpdlvlflqlqladaakrgafgheryengafqeralrcfhqlmkdttlnwkmvdasks
ieavhedirvlsedaiatatekplkelwk