PDB entry 1e9b

View 1e9b on RCSB PDB site
Description: Human thymidylate kinase complexed with AZTMP and APPNP
Class: transferase
Keywords: phosphotransferase, thymidylate kinase, p-loop, transferase
Deposited on 2000-10-10, released 2001-10-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-24, with a file datestamp of 2019-07-19.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: thymidylate kinase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1E9B
      • engineered mutation (202)
      • conflict (185)
      • conflict (192)
      • conflict (186)
      • conflict (193)
    • Uniprot P23919 (Start-214)
    Domains in SCOPe 2.08: d1e9ba_
  • Heterogens: ATM, ADP, ANP, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1e9bA (A:)
gshmaarrgalivlegvdragkstqsrklvealcaaghraellrfpersteigkllssyl
qkksdvedhsvhllfsanrweqvplikeklsqgvtlvvdryafsgvaftgakenfsldwc
kqpdvglpkpdlvlflqlqladaakrgafgheryengafqeralrcfhqlmkdttlnwkm
vdasksieavhedirvlsedaiatatekplgelwk

    Sequence, based on observed residues (ATOM records): (download) 
    >1e9bA (A:)
rrgalivlegvdragkstqsrklvealcaaghraellrfpersteigkllssylqkksdv
edhsvhllfsanrweqvplikeklsqgvtlvvdryafsgvaftgakenfsldwckqpdvg
lpkpdlvlflqlqladaakrgafgheryengafqeralrcfhqlmkdttlnwkmvdasks
ieavhedirvlsedaiatatekplgelwk