PDB entry 1e8x

View 1e8x on RCSB PDB site
Description: structural insights into phoshoinositide 3-kinase enzymatic mechanism and signalling
Deposited on 2000-10-03, released 2000-10-26
The last revision prior to the SCOP 1.59 freeze date was dated 2000-11-17, with a file datestamp of 2000-11-17.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.255
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1e8xA (A:)
aaseetlafqrqlnaligydvtdvsnvhddeleftrrrlvtprmaevagrdpklyamhpw
vtskplpeyllkkitnncvfivihrsttsqtikvsaddtpgtilqsfftkmakkkslmdi
pesqnerdfvlrvcgrdeylvgetpiknfqwvrqclkngeeihlvldtppdpaldevrke
ewplvddctgvtgyheqltihgkdhesvftvslwdcdrkfrvkirgidipvlprtadltv
fveaniqygqqvlcqrrtspkpfteevlwnvwlefsikikdlpkgallnlqiycgkapal
sgktsaempspeskgkaqllyyvnlllidhrfllrhgeyvlhmwqlsgkgedqgsfnadk
ltsatnpdkensmsisilldnychpialpkhrptpdpegdrvraempnqlrkqleaiiat
dplnpltaedkellwhfryeslkdpkaypklfssvkwgqqeivaktyqllakrevwdqsa
ldvgltmqlldcnfsdenvraiavqklesledddvlhyllqlvqavkfepyhdsalarfl
lkrglrnkrighflfwflrseiaqsrhyqqrfavileaylrgcgtamlhdftqqvqvidm
lqkvtidikslsaekydvssqvisqlkqklenlqnlnlpqsfrvpydpglkagalviekc
kvmaskkkplwlefkcadptalsnetigiifkhgddlrqdmlilqilrimesiwetesld
lcllpygcistgdkigmieivkdattiakiqqstvgntgafkdevlshwlkekcpieekf
qaaverfvyscagycvatfvlgigdrhndnimisetgnlfhidfghilgnyksflginke
rvpfvltpdflfvmgtsgkktslhfqkfqdvcvkaylalrhhtnlliilfsmmlmtgmpq
ltskedieyirdaltvgkseedakkyfldqievcrdkgwtvqfnwflhlvl

    Sequence, based on observed residues (ATOM records): (download) 
    >1e8xA (A:)
aaseetlafqrqlnaligydvtdvsnvhddeleftrrrlvtprmaevagrdpklyamhpw
vtskplpeyllkkitnncvfivihrsttsqtikvsaddtpgtilqsfftkmanerdfvlr
vcgrdeylvgetpiknfqwvrqclkngeeihlvldtppdpaldevrkecdrkfrvkirgi
dipvlprtadltvfveaniqygqqvlcqrrtspkpfteevlwnvwlefsikikdlpkgal
lnlqiycqllyyvnlllidhrfllrhgeyvlhmwqlsgfnadkltsatnpdkensmsisi
lldnhpialempnqlrkqleaiiatdplnpltaedkellwhfryeslkdpkaypklfssv
kwgqqeivaktyqllakrevwdqsaldvgltmqlldcnfsdenvraiavqklesledddv
lhyllqlvqavkfepyhdsalarfllkrglrnkrighflfwflrseiaqsrhyqqrfavi
leaylrgcgtamlhdftqqvqvidmlqkvtidikslsaekydvssqvisqlkqklenlqn
lnlpqsfrvpydpglkagalviekckvmaskkkplwlefkcadptalsnetigiifkhgd
dlrqdmlilqilrimesiwetesldlcllpygcistgdkigmieivkdattiakiqqstv
gntgafkdevlshwlkekcpieekfqaaverfvyscagycvatfvlgigdrhndnimise
tgnlfhidfghvpfvltpdflfvmgtsgkktslhfqkfqdvcvkaylalrhhtnlliilf
smmlmtgmpqltskedieyirdaltvgkseedakkyfldqievcrdkgwtvqfnwflhlv
l