PDB entry 1e8n

View 1e8n on RCSB PDB site
Description: prolyl oligopeptidase from porcine brain, mutant, complexed with peptide
Class: hydrolase/hydrolase inhibitor
Keywords: hydrolase, prolyl oligopeptidase, amnesia, alpha/beta-hydrolase, beta-propeller, hydrolase-hydrolase inhibitor complex
Deposited on 2000-09-27, released 2001-01-16
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-12-28, with a file datestamp of 2016-12-22.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: prolyl endopeptidase
    Species: SUS SCROFA [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23687 (0-709)
      • engineered mutation (553)
    Domains in SCOPe 2.07: d1e8na1, d1e8na2
  • Chain 'I':
    Compound: peptide inhibitor
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 1E8N (0-End)
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1e8nA (A:)
mlsfqypdvyrdetaiqdyhghkvcdpyawledpdseqtkafveaqnkitvpfleqcpir
glykermtelydypkyschfkkgkryfyfyntglqnqrvlyvqdslegearvfldpnils
ddgtvalrgyafsedgeyfayglsasgsdwvtikfmkvdgakelpdvlervkfscmawth
dgkgmfynaypqqdgksdgtetstnlhqklyyhvlgtdqsedilcaefpdepkwmggael
sddgryvllsiregcdpvnrlwycdlqqesngitgilkwvklidnfegeydyvtnegtvf
tfktnrhspnyrlinidftdpeeskwkvlvpehekdvlewvacvrsnflvlcylhdvknt
lqlhdlatgallkifplevgsvvgysgqkkdteifyqftsflspgiiyhcdltkeelepr
vfrevtvkgidasdyqtvqifypskdgtkipmfivhkkgikldgshpaflygyggfnisi
tpnysvsrlifvrhmggvlavanirgggeygetwhkggilankqncfddfqcaaeylike
gytspkrltingganggllvatcanqrpdlfgcviaqvgvmdmlkfhkytighawttdyg
csdskqhfewlikysplhnvklpeaddiqypsmllltadhddrvvplhslkfiatlqyiv
grsrkqnnpllihvdtkaghgagkptakvieevsdmfafiarclnidwip

  • Chain 'I':
    No sequence available.