PDB entry 1e8c

View 1e8c on RCSB PDB site
Description: Structure of MurE the UDP-N-acetylmuramyl tripeptide synthetase from E. coli
Class: ligase
Keywords: ligase, peptidoglycan biosynthesis
Deposited on 2000-09-19, released 2001-09-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-08, with a file datestamp of 2019-05-03.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: udp-n-acetylmuramoylalanyl-d-glutamate--2,6-diaminopimelate ligase
    Species: Escherichia coli [TaxId:562]
    Gene: MURE
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22188 (Start-493)
      • expression tag (494-497)
    Domains in SCOPe 2.08: d1e8ca1, d1e8ca2, d1e8ca3, d1e8ca4
  • Chain 'B':
    Compound: udp-n-acetylmuramoylalanyl-d-glutamate--2,6-diaminopimelate ligase
    Species: Escherichia coli [TaxId:562]
    Gene: MURE
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22188 (Start-493)
      • expression tag (494-497)
    Domains in SCOPe 2.08: d1e8cb1, d1e8cb2, d1e8cb3, d1e8cb4
  • Heterogens: CL, UAG, API, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1e8cA (A:)
adrnlrdllapwvpdapsralremtldsrvaaagdlfvavvghqadgrryipqaiaqgva
aiiaeakdeatdgeiremhgvpviylsqlnerlsalagrfyhepsdnlrlvgvtgtngkt
tttqllaqwsqllgeisavmgtvgngllgkviptenttgsavdvqhelaglvdqgatfca
mevsshglvqhrvaalkfaasvftnlsrdhldyhgdmehyeaakwllysehhcgqaiina
ddevgrrwlaklpdavavsmedhinpnchgrwlkatevnyhdsgatirfssswgdgeies
hlmgafnvsnlllalatllalgypladllktaarlqpvcgrmevftapgkptvvvdyaht
pdalekalqaarlhcagklwcvfgcggdrdkgkrplmgaiaeefadvavvtddnprteep
raiindilagmldaghakvmegraeavtcavmqakendvvlvagkghedyqivgnqrldy
sdrvtvarllgviarshh

    Sequence, based on observed residues (ATOM records): (download) 
    >1e8cA (A:)
rnlrdllapwvpdapsralremtldsrvaaagdlfvavvghqadgrryipqaiaqgvaai
iaeakdeatdgeiremhgvpviylsqlnerlsalagrfyhepsdnlrlvgvtgtngkttt
tqllaqwsqllgeisavmgtvgngllgkviptenttgsavdvqhelaglvdqgatfcame
vsshglvqhrvaalkfaasvftnlsrdhldyhgdmehyeaakwllysehhcgqaiinadd
evgrrwlaklpdavavsmedhinpnchgrwlkatevnyhdsgatirfssswgdgeieshl
mgafnvsnlllalatllalgypladllktaarlqpvcgrmevftapgkptvvvdyahtpd
alekalqaarlhcagklwcvfgcggdrdkgkrplmgaiaeefadvavvtddnprteepra
iindilagmldaghakvmegraeavtcavmqakendvvlvagkghedyqivgnqrldysd
rvtvarllgviarshh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1e8cB (B:)
adrnlrdllapwvpdapsralremtldsrvaaagdlfvavvghqadgrryipqaiaqgva
aiiaeakdeatdgeiremhgvpviylsqlnerlsalagrfyhepsdnlrlvgvtgtngkt
tttqllaqwsqllgeisavmgtvgngllgkviptenttgsavdvqhelaglvdqgatfca
mevsshglvqhrvaalkfaasvftnlsrdhldyhgdmehyeaakwllysehhcgqaiina
ddevgrrwlaklpdavavsmedhinpnchgrwlkatevnyhdsgatirfssswgdgeies
hlmgafnvsnlllalatllalgypladllktaarlqpvcgrmevftapgkptvvvdyaht
pdalekalqaarlhcagklwcvfgcggdrdkgkrplmgaiaeefadvavvtddnprteep
raiindilagmldaghakvmegraeavtcavmqakendvvlvagkghedyqivgnqrldy
sdrvtvarllgviarshh

    Sequence, based on observed residues (ATOM records): (download) 
    >1e8cB (B:)
drnlrdllapwvpdapsralremtldsrvaaagdlfvavvghqadgrryipqaiaqgvaa
iiaeakdeatdgeiremhgvpviylsqlnerlsalagrfyhepsdnlrlvgvtgtngktt
ttqllaqwsqllgeisavmgtvgngllgkviptenttgsavdvqhelaglvdqgatfcam
evsshglvqhrvaalkfaasvftnlsrdhldyhgdmehyeaakwllysehhcgqaiinad
devgrrwlaklpdavavsmedhinpnchgrwlkatevnyhdsgatirfssswgdgeiesh
lmgafnvsnlllalatllalgypladllktaarlqpvcgrmevftapgkptvvvdyahtp
dalekalqaarlhcagklwcvfgcggdrdkgkrplmgaiaeefadvavvtddnprteepr
aiindilagmldaghakvmegraeavtcavmqakendvvlvagkghedyqivgnqrldys
drvtvarllgviarshh