PDB entry 1e7u

View 1e7u on RCSB PDB site
Description: structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, ly294002, quercetin, myricetin and staurosporine
Deposited on 2000-09-08, released 2000-11-17
The last revision prior to the SCOP 1.65 freeze date was dated 2000-12-01, with a file datestamp of 2000-12-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.254
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1e7uA (A:)
aaseetlafqrqlnaligydvtdvsnvhddeleftrrrlvtprmaevagrdpklyamhpw
vtskplpeyllkkitnncvfivihrsttsqtikvsaddtpgtilqsfftkmakkkslmdi
pesqnerdfvlrvcgrdeylvgetpiknfqwvrqclkngeeihlvldtppdpaldevrke
ewplvddctgvtgyheqltihgkdhesvftvslwdcdrkfrvkirgidipvlprtadltv
fveaniqygqqvlcqrrtspkpfteevlwnvwlefsikikdlpkgallnlqiycgakpal
sgktsaempspeskgakqllyyvnlllidhrfllrhgeyvlhmwqlsgkgedqgsfnadk
ltsatnpdkensmsisilldnychpialpkhrptpdpegdrvraempnqlrkqleaiiat
dplnpltaedkellwhfryeslkdpkaypklfssvkwgqqeivaktyqllakrevwdqsa
ldvgltmqlldcnfsdenvraiavqklesledddvlhyllqlvqavkfepyhdsalarfl
lkrglrnkrighflfwflrseiaqsrhyqqrfavileaylrgcgtamlhdftqqvqvidm
lqkvtidikslsaekydvssqvisqlkqklenlqnlnlpqsfrvpydpglkagalviekc
kvmaskkkplwlefkcadptalsnetigiifkhgddlrqdmlilqilrimesiwetesld
lcllpygcistgdkigmieivkdattiakiqqstvgntgafkdevlshwlkekcpieekf
qaaverfvyscagycvatfvlgigdrhndnimisetgnlfhidfghilgnyksflginke
rvpfvltpdflfvmgtsgkktslhfqkfqdvcvkaylalrhhtnlliilfsmmlmtgmpq
ltskedieyirdaltvgkseedakkyfldqievcrdkgwtvqfnwflhlvlgikqgekhs
a

    Sequence, based on observed residues (ATOM records): (download) 
    >1e7uA (A:)
aseetlafqrqlnaligydvtdvsnvhddeleftrrrlvtprmaevagrdpklyamhpwv
tskplpeyllkkitnncvfivihrsttsqtikvsaddtpgtilqsfftkmaknerdfvlr
vcgrdeylvgetpiknfqwvrqclkngeeihlvldtppdpaldevrketvslwdcdrkfr
vkirgidipvlprtadltvfveaniqygqqvlcqrrtspkpfteevlwnvwlefsikikd
lpkgallnlqiycgakqllyyvnlllidhrfllrhgeyvlhmwqlsgkgfnadkltsatn
pdkensmsisilldnychpialpkhrptdrvraempnqlrkqleaiiatdplnpltaedk
ellwhfryeslkdpkaypklfssvkwgqqeivaktyqllakrevwdqsaldvgltmqlld
cnfsdenvraiavqklesledddvlhyllqlvqavkfepyhdsalarfllkrglrnkrig
hflfwflrseiaqsrhyqqrfavileaylrgcgtamlhdftqqvqvidmlqkvtidiksl
saekydvssqvisqlkqklenlqnlnlpqsfrvpydpglkagalviekckvmaskkkplw
lefkcadptalsnetigiifkhgddlrqdmlilqilrimesiwetesldlcllpygcist
gdkigmieivkdattiakiqqstvgntgafkdevlshwlkekcpieekfqaaverfvysc
agycvatfvlgigdrhndnimisetgnlfhidfghinkervpfvltpdflfvmgtsgkkt
slhfqkfqdvcvkaylalrhhtnlliilfsmmlmtgmpqltskedieyirdaltvgksee
dakkyfldqievcrdkgwtvqfnwflhlvlgi