PDB entry 1e7a

View 1e7a on RCSB PDB site
Description: crystal structure of human serum albumin complexed with the general anesthetic propofol
Class: carrier protein
Keywords: carrier protein, albumin, general anesthetic, propofol
Deposited on 2000-08-26, released 2001-01-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.248
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serum albumin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1e7aa1, d1e7aa2, d1e7aa3
  • Chain 'B':
    Compound: serum albumin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1e7ab1, d1e7ab2, d1e7ab3
  • Heterogens: PFL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1e7aA (A:)
dahksevahrfkdlgeenfkalvliafaqylqqcpfedhvklvnevtefaktcvadesae
ncdkslhtlfgdklctvatlretygemadccakqepernecflqhkddnpnlprlvrpev
dvmctafhdneetflkkylyeiarrhpyfyapellffakrykaafteccqaadkaacllp
kldelrdegkassakqrlkcaslqkfgerafkawavarlsqrfpkaefaevsklvtdltk
vhtecchgdllecaddradlakyicenqdsissklkeccekpllekshciaevendempa
dlpslaadfveskdvcknyaeakdvflgmflyeyarrhpdysvvlllrlaktyettlekc
caaadphecyakvfdefkplveepqnlikqncelfeqlgeykfqnallvrytkkvpqvst
ptlvevsrnlgkvgskcckhpeakrmpcaedylsvvlnqlcvlhektpvsdrvtkcctes
lvnrrpcfsalevdetyvpkefnaetftfhadictlsekerqikkqtalvelvkhkpkat
keqlkavmddfaafvekcckaddketcfaeegkklvaasqaalgl

    Sequence, based on observed residues (ATOM records): (download) 
    >1e7aA (A:)
sevahrfkdlgeenfkalvliafaqylqqcpfedhvklvnevtefaktcvadesaencdk
slhtlfgdklctvatlretygemadccakqepernecflqhkddnpnlprlvrpevdvmc
tafhdneetflkkylyeiarrhpyfyapellffakrykaafteccqaadkaacllpklde
lrdegkassakqrlkcaslqkfgerafkawavarlsqrfpkaefaevsklvtdltkvhte
cchgdllecaddradlakyicenqdsissklkeccekpllekshciaevendempadlps
laadfveskdvcknyaeakdvflgmflyeyarrhpdysvvlllrlaktyettlekccaaa
dphecyakvfdefkplveepqnlikqncelfeqlgeykfqnallvrytkkvpqvstptlv
evsrnlgkvgskcckhpeakrmpcaedylsvvlnqlcvlhektpvsdrvtkccteslvnr
rpcfsalevdetyvpkefnaetftfhadictlsekerqikkqtalvelvkhkpkatkeql
kavmddfaafvekcckaddketcfaeegkklvaasqaa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1e7aB (B:)
dahksevahrfkdlgeenfkalvliafaqylqqcpfedhvklvnevtefaktcvadesae
ncdkslhtlfgdklctvatlretygemadccakqepernecflqhkddnpnlprlvrpev
dvmctafhdneetflkkylyeiarrhpyfyapellffakrykaafteccqaadkaacllp
kldelrdegkassakqrlkcaslqkfgerafkawavarlsqrfpkaefaevsklvtdltk
vhtecchgdllecaddradlakyicenqdsissklkeccekpllekshciaevendempa
dlpslaadfveskdvcknyaeakdvflgmflyeyarrhpdysvvlllrlaktyettlekc
caaadphecyakvfdefkplveepqnlikqncelfeqlgeykfqnallvrytkkvpqvst
ptlvevsrnlgkvgskcckhpeakrmpcaedylsvvlnqlcvlhektpvsdrvtkcctes
lvnrrpcfsalevdetyvpkefnaetftfhadictlsekerqikkqtalvelvkhkpkat
keqlkavmddfaafvekcckaddketcfaeegkklvaasqaalgl

    Sequence, based on observed residues (ATOM records): (download) 
    >1e7aB (B:)
sevahrfkdlgeenfkalvliafaqylqqcpfedhvklvnevtefaktcvadesaencdk
slhtlfgdklctvatlretygemadccakqepernecflqhkddnpnlprlvrpevdvmc
tafhdneetflkkylyeiarrhpyfyapellffakrykaafteccqaadkaacllpklde
lrdegkassakqrlkcaslqkfgerafkawavarlsqrfpkaefaevsklvtdltkvhte
cchgdllecaddradlakyicenqdsissklkeccekpllekshciaevendempadlps
laadfveskdvcknyaeakdvflgmflyeyarrhpdysvvlllrlaktyettlekccaaa
dphecyakvfdefkplveepqnlikqncelfeqlgeykfqnallvrytkkvpqvstptlv
evsrnlgkvgskcckhpeakrmpcaedylsvvlnqlcvlhektpvsdrvtkccteslvnr
rpcfsalevdetyvpkefnaetftfhadictlsekerqikkqtalvelvkhkpkatkeql
kavmddfaafvekcckaddketcfaeegkklvaasqaa