PDB entry 1e4w

View 1e4w on RCSB PDB site
Description: crossreactive binding of a circularized peptide to an anti-tgfalpha antibody fab-fragment
Class: complex (antibody/antigen)
Keywords: cross-reactivity, protein-peptide recognition
Deposited on 2000-07-12, released 2001-07-12
The last revision prior to the SCOP 1.75 freeze date was dated 2005-04-05, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.204
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: tab2
    Species: Mus musculus
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1e4wh1, d1e4wh2
  • Chain 'L':
    Compound: tab2
    Species: Mus musculus
    Domains in SCOP 1.75: d1e4wl1, d1e4wl2
  • Chain 'P':
    Compound: cyclic peptide
  • Heterogens: NI, CL, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1e4wH (H:)
qvqlqqpgaelvkpgasvklsckasgftftnywmhwvkqrpgqglewigeilpsngrtny
nekfktkatltvdkssntaymqlssltsedsavyycarspsdywgqgttltvssakttap
svyplapvcgdttgssvtlgclvkgyfpepvtltwnsgslssgvhtfpavlqsdlytlss
svtvtsstwpsqsitcnvahpasstkvdkkiep

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1e4wL (L:)
diqmtqtpsslsaslgdrvtiscrasqdishylnwfqqkpdgtvklliyytstlhsgvps
rfsgsgsgtdysltisnleeediafyfcqqggalpftfgsgtklaikradaaptvsifpp
sseqltsggasvvcflnnfypkdinvkwkidgserqngvldswtdqdskdstysmsstlt
ltkdeyerhnsytceathktstspivksfnrnec

  • Chain 'P':
    No sequence available.