PDB entry 1e3c

View 1e3c on RCSB PDB site
Description: Crystal structure of an Arylsulfatase A mutant C69S soaked in synthetic substrate
Class: hydrolase
Keywords: hydrolase, cerebroside-3-sulfate hydrolysis, lysosomal enzyme, formylglycine
Deposited on 2000-06-13, released 2001-03-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'P':
    Compound: arylsulfatase a
    Species: Homo sapiens [TaxId:9606]
    Gene: ARSA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15289 (0-End)
      • engineered mutation (50)
      • conflict (196)
    Domains in SCOPe 2.08: d1e3cp_
  • Heterogens: MG, HOH

PDB Chain Sequences:

  • Chain 'P':
    Sequence, based on SEQRES records: (download) 
    >1e3cP (P:)
rppnivlifaddlgygdlgcyghpssttpnldqlaagglrftdfyvpvslstpsraallt
grlpvrmgmypgvlvpssrgglpleevtvaevlaargyltgmagkwhlgvgpegaflpph
qgfhrflgipyshdqgpcqnltcfppatpcdggcdqglvpipllanlsveaqppwlpgle
arymafahdlmadaqredrpfflyyashhthypqfsgqsfaersgrgpfgdslmeldaav
gtlmtaigdlglleetlviftadngpetmrmsrggcsgllrcgkgttyeggvrepalafw
pghiapgvthelassldllptlaalagaplpnvtldgfdlsplllgtgksprqslffyps
ypdevrgvfavrtgkykahfftqgsahsdttadpachasssltaheppllydlskdpgen
ynllggvagatpevlqalkqlqllkaqldaavtfgpsqvargedpalqicchpgctprpa
cchcpdpha

    Sequence, based on observed residues (ATOM records): (download) 
    >1e3cP (P:)
rppnivlifaddlgygdlgcyghpssttpnldqlaagglrftdfyvpvslstpsraallt
grlpvrmgmypgvlvpssrgglpleevtvaevlaargyltgmagkwhlgvgpegaflpph
qgfhrflgipyshdqgpcqnltcfppatpcdggcdqglvpipllanlsveaqppwlpgle
arymafahdlmadaqredrpfflyyashhthypqfsgqsfaersgrgpfgdslmeldaav
gtlmtaigdlglleetlviftadngpetmrmsrggcsgllrcgkgttyeggvrepalafw
pghiapgvthelassldllptlaalagaplpnvtldgfdlsplllgtgksprqslffyps
ypdevrgvfavrtgkykahfftqgsahsdttadpachasssltaheppllydlskdpgen
ynllgatpevlqalkqlqllkaqldaavtfgpsqvargedpalqicchpgctprpacchc
p