PDB entry 1e3a

View 1e3a on RCSB PDB site
Description: A slow processing precursor penicillin acylase from Escherichia coli
Class: antibiotic resistance
Keywords: antibiotic resistance, amidase, ntn-hydrolase, hydrolysis of penicillin g acylase
Deposited on 2000-06-07, released 2000-11-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-24, with a file datestamp of 2019-07-19.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: penicillin amidase alpha subunit
    Species: Escherichia coli [TaxId:562]
    Gene: PAC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1e3a.1
  • Chain 'B':
    Compound: penicillin amidase beta subunit
    Species: Escherichia coli [TaxId:562]
    Gene: PAC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06875 (0-559)
      • engineered mutation (2)
    Domains in SCOPe 2.08: d1e3a.1
  • Heterogens: CA, CL, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1e3aA (A:)
eqssseikivrdeygmphiyandtwhlfygygyvvaqdrlfqmemarrstqgtvaevlgk
dfvkfdkdirrnywpdairaqiaalspedmsilqgyadgmnawidkvntnpetllpkqfn
tfgftpkrwepfdvamifvgtmanrfsdstseidnlalltalkdkygvsqgmavfnqlkw
lvnpsapttiavqesnyplkfnqqnsqtaallprydlpapmldrpakgadgallalaagk
nretiaaqfaqgganglagy

    Sequence, based on observed residues (ATOM records): (download) 
    >1e3aA (A:)
ssseikivrdeygmphiyandtwhlfygygyvvaqdrlfqmemarrstqgtvaevlgkdf
vkfdkdirrnywpdairaqiaalspedmsilqgyadgmnawidkvntnpetllpkqfntf
gftpkrwepfdvamifvgtmanrfsdstseidnlalltalkdkygvsqgmavfnqlkwlv
npsapttiavqesnyplkfnqqnsqtaallprydlpapmldrpakgadgallalaagknr
etiaaqfaqgganglagy

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1e3aB (B:)
ptgsnmwvigkskaqdakaimvngpqfgwyapaytygiglhgagydvtgntpfaypglvf
ghngviswgstagfgddvdifaerlsaekpgyylhngkwvkmlsreetitvkngqaetft
vwrtvhgnilqtdqttqtayaksrawdgkevasllawthqmkaknwqewtqqaakqalti
nwyyadvngnigyvhtgaypdrqsghdprlpvpgtgkwdwkgllpfemnpkvynpqsgyi
anwnnspqkdypasdlfaflwggadrvteidrlleqkprltadqawdvirqtsrqdlnlr
lflptlqaatsgltqsdprrqlvetltrwdginllnddgktwqqpgsailnvwltsmlkr
tvvaavpmpfdkwysasgyettqdgptgslnisvgakilyeavqgdkspipqavdlfagk
pqqevvlaaledtwetlskrygnnvsnwktpamaltfrannffgvpqaaaeetrhqaeyq
nrgtendmivfspttsdrpvlawdvvapgqsgfiapdgtvdkhyedqlkmyenfgrkslw
ltkqdveahkesqevlhvqr