PDB entry 1e33

View 1e33 on RCSB PDB site
Description: Crystal structure of an Arylsulfatase A mutant P426L
Class: hydrolase
Keywords: hydrolase, cerebroside-3-sulfate hydrolysis, lysosomal enzyme, formylglycine
Deposited on 2000-06-06, released 2001-05-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'P':
    Compound: arylsulfatase a
    Species: Homo sapiens [TaxId:9606]
    Gene: ARSA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15289 (0-End)
      • conflict (196)
      • engineered mutation (407)
    Domains in SCOPe 2.08: d1e33p_
  • Heterogens: MG, HOH

PDB Chain Sequences:

  • Chain 'P':
    Sequence, based on SEQRES records: (download) 
    >1e33P (P:)
rppnivlifaddlgygdlgcyghpssttpnldqlaagglrftdfyvpvslxtpsraallt
grlpvrmgmypgvlvpssrgglpleevtvaevlaargyltgmagkwhlgvgpegaflpph
qgfhrflgipyshdqgpcqnltcfppatpcdggcdqglvpipllanlsveaqppwlpgle
arymafahdlmadaqredrpfflyyashhthypqfsgqsfaersgrgpfgdslmeldaav
gtlmtaigdlglleetlviftadngpetmrmsrggcsgllrcgkgttyeggvrepalafw
pghiapgvthelassldllptlaalagaplpnvtldgfdlsplllgtgksprqslffyps
ypdevrgvfavrtgkykahfftqgsahsdttadpachasssltaheplllydlskdpgen
ynllggvagatpevlqalkqlqllkaqldaavtfgpsqvargedpalqicchpgctprpa
cchcpdpha

    Sequence, based on observed residues (ATOM records): (download) 
    >1e33P (P:)
rppnivlifaddlgygdlgcyghpssttpnldqlaagglrftdfyvpvslxtpsraallt
grlpvrmgmypgvlvpssrgglpleevtvaevlaargyltgmagkwhlgvgpegaflpph
qgfhrflgipyshdqgpcqnltcfppatpcdggcdqglvpipllanlsveaqppwlpgle
arymafahdlmadaqredrpfflyyashhthypqfsgqsfaersgrgpfgdslmeldaav
gtlmtaigdlglleetlviftadngpetmrmsrggcsgllrcgkgttyeggvrepalafw
pghiapgvthelassldllptlaalagaplpnvtldgfdlsplllgtgksprqslffyps
ypdevrgvfavrtgkykahfftqgsahsdttadpachasssltaheplllydlskdpgen
ynllgatpevlqalkqlqllkaqldaavtfgpsqvargedpalqicchpgctprpacchc
p