PDB entry 1e2f

View 1e2f on RCSB PDB site
Description: human thymidylate kinase complexed with thymidine monophosphate, adenosine diphosphate and a magnesium-ion
Class: transferase
Keywords: transferase, treansferase, p-loop
Deposited on 2000-05-22, released 2001-05-17
The last revision prior to the SCOPe 2.07 freeze date was dated 2010-12-15, with a file datestamp of 2010-12-10.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.21
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: thymidylate kinase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1E2F
      • engineered mutation (202)
      • conflict (185-186)
      • conflict (192-193)
    • Uniprot P23919 (Start-214)
    Domains in SCOPe 2.07: d1e2fa_
  • Heterogens: TMP, ANP, ADP, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1e2fA (A:)
gshmaarrgalivlegvdragkstqsrklvealcaaghraellrfpersteigkllssyl
qkksdvedhsvhllfsanrweqvplikeklsqgvtlvvdryafsgvaftgakenfsldwc
kqpdvglpkpdlvlflqlqladaakrgafgheryengafqeralrcfhqlmkdttlnwkm
vdasksieavhedirvlsedaiatatekplgelwk

    Sequence, based on observed residues (ATOM records): (download) 
    >1e2fA (A:)
arrgalivlegvdragkstqsrklvealcaaghraellrfpersteigkllssylqkksd
vedhsvhllfsanrweqvplikeklsqgvtlvvdryafsgvaftgakenfsldwckqpdv
glpkpdlvlflqlqladaakrgafgheryengafqeralrcfhqlmkdttlnwkmvdask
sieavhedirvlsedaiatatekplgelwk