PDB entry 1e1x

View 1e1x on RCSB PDB site
Description: human cyclin dependent kinase 2 complexed with the inhibitor nu6027
Class: protein kinase
Keywords: protein kinase, cell cycle, phosphorylation, cell division, mitosis, inhibition
Deposited on 2000-05-11, released 2001-05-10
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.213
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cyclin-dependent protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1E1X
    • Uniprot P24941 (0-297)
    Domains in SCOPe 2.07: d1e1xa_
  • Heterogens: NW1, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1e1xA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >1e1xA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkivpstaireisllkelnhpnivklld
    vihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdl
    kpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyystavdiws
    lgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdf
    skvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl