PDB entry 1e1c

View 1e1c on RCSB PDB site
Description: METHYLMALONYL-COA MUTASE H244A Mutant
Class: isomerase
Keywords: isomerase, mutase, intramolecular transferase
Deposited on 2000-04-30, released 2000-05-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-06-28, with a file datestamp of 2017-06-23.
Experiment type: XRAY
Resolution: 2.62 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: methylmalonyl-coa mutase alpha chain
    Species: PROPIONIBACTERIUM FREUDENREICHII SUBSP. SHERMANII [TaxId:1752]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11653 (0-726)
      • engineered mutation (242)
    Domains in SCOPe 2.08: d1e1ca1, d1e1ca2
  • Chain 'B':
    Compound: methylmalonyl-coa mutase beta chain
    Species: PROPIONIBACTERIUM FREUDENREICHII SUBSP. SHERMANII [TaxId:1752]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11652 (Start-636)
      • see remark 999 (201)
      • see remark 999 (328-329)
    Domains in SCOPe 2.08: d1e1cb1, d1e1cb2
  • Chain 'C':
    Compound: methylmalonyl-coa mutase alpha chain
    Species: PROPIONIBACTERIUM FREUDENREICHII SUBSP. SHERMANII [TaxId:1752]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11653 (0-726)
      • engineered mutation (242)
    Domains in SCOPe 2.08: d1e1cc1, d1e1cc2
  • Chain 'D':
    Compound: methylmalonyl-coa mutase beta chain
    Species: PROPIONIBACTERIUM FREUDENREICHII SUBSP. SHERMANII [TaxId:1752]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11652 (Start-636)
      • see remark 999 (201)
      • see remark 999 (328-329)
    Domains in SCOPe 2.08: d1e1cd1, d1e1cd2
  • Heterogens: B12, DCA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1e1cA (A:)
stlprfdsvdlgnapvpadaarrfeelaakagtgeawetaeqipvgtlfnedvykdmdwl
dtyagippfvhgpyatmyafrpwtirqyagfstakesnafyrrnlaagqkglsvafdlpt
hrgydsdnprvagdvgmagvaidsiydmrelfagipldqmsvsmtmngavlpilalyvvt
aeeqgvkpeqlagtiqndilkefmvrntyiyppqpsmriiseifaytsanmpkwnsisis
gyamqeagatadiemaytladgvdyiragesvglnvdqfaprlsffwgigmnffmevakl
raarmlwaklvhqfgpknpksmslrthsqtsgwsltaqdvynnvvrtcieamaatqghtq
slhtnsldeaialptdfsariarntqlflqqesgttrvidpwsgsayveeltwdlarkaw
ghiqevekvggmakaiekgipkmrieeaaartqaridsgrqpligvnkyrleheppldvl
kvdnstvlaeqkaklvklraerdpekvkaaldkitwaagnpddkdpdrnllklcidagra
matvgemsdalekvfgrytaqirtisgvyskevkntpeveearelveefeqaegrrpril
lakmgqdghdrgqkviatayadlgfdvdvgplfqtpeetarqaveadvhvvgvsslaggh
ltlvpalrkeldklgrpdilitvggvipeqdfdelrkdgaveiytpgtvipesaislvkk
lraslda

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1e1cB (B:)
sstdqgtnpadtddltpttlslagdfpkateeqwerevekvlnrgrppekqltfaeclkr
ltvhtvdgidivpmyrpkdapkklgypgvapftrgttvrngdmdawdvralhedpdekft
rkaileglergvtslllrvdpdaiapehldevlsdvllemtkvevfsrydqgaaaealvs
vyersdkpakdlalnlgldpigfaalqgtepdltvlgdwvrrlakfspdsravtidaniy
hnagagdvaelawalatgaeyvralveqgftateafdtinfrvtathdqfltiarlralr
eawarigevfgvdedkrgarqnaitswreltredpyvnilrgsiatfsasvggaesittl
pftqalglpeddfplriarntgivlaeevnigrvndpaggsyyvesltrsladaawkefq
eveklggmskavmtehvtkvldacnaerakrlanrkqpitavsefpmigarsietkpfpa
aparkglawhrdsevfeqlmdrstsvserpkvflaclgtrrdfggregfsspvwhiagid
tpqveggttaeiveafkksgaqvadlcssakvyaqqglevakalkaagakalylsgafke
fgddaaeaeklidgrlfmgmdvvdtlsstldilgvak

    Sequence, based on observed residues (ATOM records): (download) 
    >1e1cB (B:)
tlslagdfpkateeqwerevekvlnrgrppekqltfaeclkrltvhtvdgidivpmyrpk
dapkklgypgvapftrgttvrngdmdawdvralhedpdekftrkaileglergvtslllr
vdpdaiapehldevlsdvllemtkvevfsrydqgaaaealvsvyersdkpakdlalnlgl
dpigfaalqgtepdltvlgdwvrrlakfspdsravtidaniyhnagagdvaelawalatg
aeyvralveqgftateafdtinfrvtathdqfltiarlralreawarigevfgvdedkrg
arqnaitswreltredpyvnilrgsiatfsasvggaesittlpftqalglpeddfplria
rntgivlaeevnigrvndpaggsyyvesltrsladaawkefqeveklggmskavmtehvt
kvldacnaerakrlanrkqpitavsefpmigarsietkpfpaaparkglawhrdsevfeq
lmdrstsvserpkvflaclgtrrdfggregfsspvwhiagidtpqveggttaeiveafkk
sgaqvadlcssakvyaqqglevakalkaagakalylsgafkefgddaaeaeklidgrlfm
gmdvvdtlsstldilgvak

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1e1cC (C:)
stlprfdsvdlgnapvpadaarrfeelaakagtgeawetaeqipvgtlfnedvykdmdwl
dtyagippfvhgpyatmyafrpwtirqyagfstakesnafyrrnlaagqkglsvafdlpt
hrgydsdnprvagdvgmagvaidsiydmrelfagipldqmsvsmtmngavlpilalyvvt
aeeqgvkpeqlagtiqndilkefmvrntyiyppqpsmriiseifaytsanmpkwnsisis
gyamqeagatadiemaytladgvdyiragesvglnvdqfaprlsffwgigmnffmevakl
raarmlwaklvhqfgpknpksmslrthsqtsgwsltaqdvynnvvrtcieamaatqghtq
slhtnsldeaialptdfsariarntqlflqqesgttrvidpwsgsayveeltwdlarkaw
ghiqevekvggmakaiekgipkmrieeaaartqaridsgrqpligvnkyrleheppldvl
kvdnstvlaeqkaklvklraerdpekvkaaldkitwaagnpddkdpdrnllklcidagra
matvgemsdalekvfgrytaqirtisgvyskevkntpeveearelveefeqaegrrpril
lakmgqdghdrgqkviatayadlgfdvdvgplfqtpeetarqaveadvhvvgvsslaggh
ltlvpalrkeldklgrpdilitvggvipeqdfdelrkdgaveiytpgtvipesaislvkk
lraslda

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1e1cD (D:)
sstdqgtnpadtddltpttlslagdfpkateeqwerevekvlnrgrppekqltfaeclkr
ltvhtvdgidivpmyrpkdapkklgypgvapftrgttvrngdmdawdvralhedpdekft
rkaileglergvtslllrvdpdaiapehldevlsdvllemtkvevfsrydqgaaaealvs
vyersdkpakdlalnlgldpigfaalqgtepdltvlgdwvrrlakfspdsravtidaniy
hnagagdvaelawalatgaeyvralveqgftateafdtinfrvtathdqfltiarlralr
eawarigevfgvdedkrgarqnaitswreltredpyvnilrgsiatfsasvggaesittl
pftqalglpeddfplriarntgivlaeevnigrvndpaggsyyvesltrsladaawkefq
eveklggmskavmtehvtkvldacnaerakrlanrkqpitavsefpmigarsietkpfpa
aparkglawhrdsevfeqlmdrstsvserpkvflaclgtrrdfggregfsspvwhiagid
tpqveggttaeiveafkksgaqvadlcssakvyaqqglevakalkaagakalylsgafke
fgddaaeaeklidgrlfmgmdvvdtlsstldilgvak

    Sequence, based on observed residues (ATOM records): (download) 
    >1e1cD (D:)
tlslagdfpkateeqwerevekvlnrgrppekqltfaeclkrltvhtvdgidivpmyrpk
dapkklgypgvapftrgttvrngdmdawdvralhedpdekftrkaileglergvtslllr
vdpdaiapehldevlsdvllemtkvevfsrydqgaaaealvsvyersdkpakdlalnlgl
dpigfaalqgtepdltvlgdwvrrlakfspdsravtidaniyhnagagdvaelawalatg
aeyvralveqgftateafdtinfrvtathdqfltiarlralreawarigevfgvdedkrg
arqnaitswreltredpyvnilrgsiatfsasvggaesittlpftqalglpeddfplria
rntgivlaeevnigrvndpaggsyyvesltrsladaawkefqeveklggmskavmtehvt
kvldacnaerakrlanrkqpitavsefpmigarsietkpfpaaparkglawhrdsevfeq
lmdrstsvserpkvflaclgtrrdfggregfsspvwhiagidtpqveggttaeiveafkk
sgaqvadlcssakvyaqqglevakalkaagakalylsgafkefgddaaeaeklidgrlfm
gmdvvdtlsstldilgvak