PDB entry 1dy8

View 1dy8 on RCSB PDB site
Description: Inhibition of the Hepatitis C Virus NS3/4A Protease. The Crystal Structures of Two Protease-Inhibitor Complexes (inhibitor II)
Class: hydrolase/hydrolase inhibitor
Keywords: serine protease, protease inhibition, hydrolase-hydrolase inhibitor complex
Deposited on 2000-01-31, released 2001-01-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-24, with a file datestamp of 2019-07-19.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protease/helicase ns3 (p70)
    Species: HEPATITIS C VIRUS (ISOLATE TAIWAN) [TaxId:31645]
    Gene: HCV
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1dy8.1
  • Chain 'B':
    Compound: protease/helicase ns3 (p70)
    Species: HEPATITIS C VIRUS (ISOLATE TAIWAN) [TaxId:31645]
    Gene: HCV
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1dy8.2
  • Chain 'C':
    Compound: nonstructural protein ns4a (p4)
    Species: HEPATITIS C VIRUS (ISOLATE TAIWAN) [TaxId:31645]
    Gene: HCV
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1dy8.1
  • Chain 'D':
    Compound: nonstructural protein ns4a (p4)
    Species: HEPATITIS C VIRUS (ISOLATE TAIWAN) [TaxId:31645]
    Gene: HCV
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1dy8.2
  • Heterogens: 0F7, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1dy8A (A:)
apitaysqqtrgllgciitsltgrdknqvdgevqvlstatqsflatcvngvcwtvyhgag
sktlagpkgpitqmytnvdqdlvgwpappgarsmtpctcgssdlylvtrhadvipvrrrg
dsrgsllsprpvsylkgssggpllcpsghvvgifraavctrgvakavdfipvesmettmr
spvftdn

    Sequence, based on observed residues (ATOM records): (download) 
    >1dy8A (A:)
apitaysqqtrgllgciitsltgrdknqvdgevqvlstatqsflatcvngvcwtvyhgag
sktlagpkgpitqmytnvdqdlvgwpappgarsmtpctcgssdlylvtrhadvipvrrrg
dsrgsllsprpvsylkgssggpllcpsghvvgifraavctrgvakavdfipvesm

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1dy8B (B:)
apitaysqqtrgllgciitsltgrdknqvdgevqvlstatqsflatcvngvcwtvyhgag
sktlagpkgpitqmytnvdqdlvgwpappgarsmtpctcgssdlylvtrhadvipvrrrg
dsrgsllsprpvsylkgssggpllcpsghvvgifraavctrgvakavdfipvesmettmr
spvftdn

    Sequence, based on observed residues (ATOM records): (download) 
    >1dy8B (B:)
apitaysqqtrgllgciitsltgrdknqvdgevqvlstatqsflatcvngvcwtvyhgag
sktlagpkgpitqmytnvdqdlvgwpappgarsmtpctcgssdlylvtrhadvipvrrrg
dsrgsllsprpvsylkgssggpllcpsghvvgifraavctrgvakavdfipvesm

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1dy8C (C:)
kgsvvivgriilsgrk

    Sequence, based on observed residues (ATOM records): (download) 
    >1dy8C (C:)
gsvvivgriils

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1dy8D (D:)
kgsvvivgriilsgrk

    Sequence, based on observed residues (ATOM records): (download) 
    >1dy8D (D:)
gsvvivgriils