PDB entry 1dx4

View 1dx4 on RCSB PDB site
Description: ache from drosophila melanogaster complex with tacrine derivative 9-(3-phenylmethylamino)-1,2,3,4-tetrahydroacridine
Class: hydrolase (serine esterase)
Keywords: hydrolase (serine esterase), hydrolase, serine esterase, synapse, membrane, nerve, muscle, signal, neurotransmitter degradation, glycoprotein, gpi-anchor, alternative splicing
Deposited on 1999-12-20, released 2000-07-21
The last revision prior to the SCOP 1.75 freeze date was dated 2000-07-21, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.22
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: acetylcholinesterase
    Species: Drosophila melanogaster
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1dx4a_
  • Heterogens: NAG, SO4, 760, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1dx4A (A:)
vidrlvvqtssgpvrgrsvtvqgrevhvytgipyakppvedlrfrkpvpaepwhgvldat
glsatcvqeryeyfpgfsgeeiwnpntnvsedclyinvwapakarlrhgrganggehpng
kqadtdhlihngnpqnttnglpiliwiygggfmtgsatldiynadimaavgnvivasfqy
rvgafgflhlapempsefaeeapgnvglwdqalairwlkdnahafggnpewmtlfgesag
sssvnaqlmspvtrglvkrgmmqsgtmnapwshmtsekaveigkalindcncnasmlktn
pahvmscmrsvdaktisvqqwnsysgilsfpsaptidgaflpadpmtlmktadlkdydil
mgnvrdegtyfllydfidyfdkddatalprdkyleimnnifgkatqaereaiifqytswe
gnpgyqnqqqigravgdhfftcptneyaqalaergasvhyyyfthrtstslwgewmgvlh
gdeieyffgqplnnslqyrpverelgkrmlsaviefaktgnpaqdgeewpnfskedpvyy
ifstddkieklargplaarcsfwndylpkvrswagtcdgdsgsas

    Sequence, based on observed residues (ATOM records): (download) 
    >1dx4A (A:)
drlvvqtssgpvrgrsvtvqgrevhvytgipyakppvedlrfrkpvpaepwhgvldatgl
satcvqeryeyfpgfsgeeiwnpntnvsedclyinvwapattnglpiliwiygggfmtgs
atldiynadimaavgnvivasfqyrvgafgflhlapempsefaeeapgnvglwdqalair
wlkdnahafggnpewmtlfgesagsssvnaqlmspvtrglvkrgmmqsgtmnapwshmts
ekaveigkalindcncnasmlktnpahvmscmrsvdaktisvqqwnsysgilsfpsapti
dgaflpadpmtlmktadlkdydilmgnvrdegtyfllydfidyfdkddatalprdkylei
mnnifgkatqaereaiifqytswegnpgyqnqqqigravgdhfftcptneyaqalaerga
svhyyyfthrtstslwgewmgvlhgdeieyffgqplnnslqyrpverelgkrmlsavief
aktgnpaqdgeewpnfskedpvyyifstddkieklargplaarcsfwndylpkvrsw