PDB entry 1dvm

View 1dvm on RCSB PDB site
Description: active form of human pai-1
Class: blood clotting
Keywords: serpin, pai-1, inhibitor, blood clotting
Deposited on 2000-01-21, released 2000-09-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-04, with a file datestamp of 2017-09-29.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: plasminogen activator inhibitor-1
    Species: Homo sapiens [TaxId:9606]
    Gene: UMBILICAL VEIN ENDOTHELIUM LIBRARY
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05121 (Start-378)
      • engineered (149)
      • engineered (153)
      • engineered (318)
      • engineered (353)
    Domains in SCOPe 2.07: d1dvma_
  • Chain 'B':
    Compound: plasminogen activator inhibitor-1
    Species: Homo sapiens [TaxId:9606]
    Gene: UMBILICAL VEIN ENDOTHELIUM LIBRARY
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05121 (Start-378)
      • engineered (149)
      • engineered (153)
      • engineered (318)
      • engineered (353)
    Domains in SCOPe 2.07: d1dvmb_
  • Chain 'C':
    Compound: plasminogen activator inhibitor-1
    Species: Homo sapiens [TaxId:9606]
    Gene: UMBILICAL VEIN ENDOTHELIUM LIBRARY
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05121 (Start-378)
      • engineered (149)
      • engineered (153)
      • engineered (318)
      • engineered (353)
    Domains in SCOPe 2.07: d1dvmc_
  • Chain 'D':
    Compound: plasminogen activator inhibitor-1
    Species: Homo sapiens [TaxId:9606]
    Gene: UMBILICAL VEIN ENDOTHELIUM LIBRARY
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05121 (Start-378)
      • engineered (149)
      • engineered (153)
      • engineered (318)
      • engineered (353)
    Domains in SCOPe 2.07: d1dvmd_
  • Heterogens: CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1dvmA (A:)
vhhppsyvahlasdfgvrvfqqvaqaskdrnvvfspygvasvlamlqlttggetqqqiqa
amgfkiddkgmapalrhlykelmgpwnkdeisttdaifvqrdlklvqgfmphffrlfrst
vkqvdfseverarfiindwvkthtkgmishllgtgavqqltrlvlvnalyfngqwktpfp
dssthrrlfhksdgstvsvpmmaqtnkfnytefttpdghyydilelpyhgdtlsmfiaap
yekevplsaltnilsaqlishwkgnmtrlprllvlpkfsletevdlrkplenlgmtdmfr
qfqadftslsdqeplhvalalqkvkievnesgtvassstavivsarmapeeiiidrpflf
vvrhnptgtvlfmgqvmep

    Sequence, based on observed residues (ATOM records): (download) 
    >1dvmA (A:)
ppsyvahlasdfgvrvfqqvaqaskdrnvvfspygvasvlamlqlttggetqqqiqaamg
fkiddkgmapalrhlykelmgpwnkdeisttdaifvqrdlklvqgfmphffrlfrstvkq
vdfseverarfiindwvkthtkgmishllgtgavqqltrlvlvnalyfngqwktpfpdss
thrrlfhksdgstvsvpmmaqtnkfnytefttpdghyydilelpyhgdtlsmfiaapyek
evplsaltnilsaqlishwkgnmtrlprllvlpkfsletevdlrkplenlgmtdmfrqfq
adftslsdqeplhvalalqkvkievnesgtvasssavivsarmapeeiiidrpflfvvrh
nptgtvlfmgqvmep

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1dvmB (B:)
vhhppsyvahlasdfgvrvfqqvaqaskdrnvvfspygvasvlamlqlttggetqqqiqa
amgfkiddkgmapalrhlykelmgpwnkdeisttdaifvqrdlklvqgfmphffrlfrst
vkqvdfseverarfiindwvkthtkgmishllgtgavqqltrlvlvnalyfngqwktpfp
dssthrrlfhksdgstvsvpmmaqtnkfnytefttpdghyydilelpyhgdtlsmfiaap
yekevplsaltnilsaqlishwkgnmtrlprllvlpkfsletevdlrkplenlgmtdmfr
qfqadftslsdqeplhvalalqkvkievnesgtvassstavivsarmapeeiiidrpflf
vvrhnptgtvlfmgqvmep

    Sequence, based on observed residues (ATOM records): (download) 
    >1dvmB (B:)
ppsyvahlasdfgvrvfqqvaqaskdrnvvfspygvasvlamlqlttggetqqqiqaamg
fkiddkgmapalrhlykelmgpwnkdeisttdaifvqrdlklvqgfmphffrlfrstvkq
vdfseverarfiindwvkthtkgmishllgtgavqqltrlvlvnalyfngqwktpfpdss
thrrlfhksdgstvsvpmmaqtnkfnytefttpdghyydilelpyhgdtlsmfiaapyek
evplsaltnilsaqlishwkgnmtrlprllvlpkfsletevdlrkplenlgmtdmfrqfq
adftslsdqeplhvalalqkvkievnesgtvamapeeiiidrpflfvvrhnptgtvlfmg
qvmep

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1dvmC (C:)
vhhppsyvahlasdfgvrvfqqvaqaskdrnvvfspygvasvlamlqlttggetqqqiqa
amgfkiddkgmapalrhlykelmgpwnkdeisttdaifvqrdlklvqgfmphffrlfrst
vkqvdfseverarfiindwvkthtkgmishllgtgavqqltrlvlvnalyfngqwktpfp
dssthrrlfhksdgstvsvpmmaqtnkfnytefttpdghyydilelpyhgdtlsmfiaap
yekevplsaltnilsaqlishwkgnmtrlprllvlpkfsletevdlrkplenlgmtdmfr
qfqadftslsdqeplhvalalqkvkievnesgtvassstavivsarmapeeiiidrpflf
vvrhnptgtvlfmgqvmep

    Sequence, based on observed residues (ATOM records): (download) 
    >1dvmC (C:)
psyvahlasdfgvrvfqqvaqaskdrnvvfspygvasvlamlqlttggetqqqiqaamgf
kiddkgmapalrhlykelmgpwnkdeisttdaifvqrdlklvqgfmphffrlfrstvkqv
dfseverarfiindwvkthtkgmishllgtgavqqltrlvlvnalyfngqwktpfpdsst
hrrlfhksdgstvsvpmmaqtnkfnytefttpdghyydilelpyhgdtlsmfiaapyeke
vplsaltnilsaqlishwkgnmtrlprllvlpkfsletevdlrkplenlgmtdmfrqfqa
dftslsdqeplhvalalqkvkievnesgsarmapeeiiidrpflfvvrhnptgtvlfmgq
vmep

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1dvmD (D:)
vhhppsyvahlasdfgvrvfqqvaqaskdrnvvfspygvasvlamlqlttggetqqqiqa
amgfkiddkgmapalrhlykelmgpwnkdeisttdaifvqrdlklvqgfmphffrlfrst
vkqvdfseverarfiindwvkthtkgmishllgtgavqqltrlvlvnalyfngqwktpfp
dssthrrlfhksdgstvsvpmmaqtnkfnytefttpdghyydilelpyhgdtlsmfiaap
yekevplsaltnilsaqlishwkgnmtrlprllvlpkfsletevdlrkplenlgmtdmfr
qfqadftslsdqeplhvalalqkvkievnesgtvassstavivsarmapeeiiidrpflf
vvrhnptgtvlfmgqvmep

    Sequence, based on observed residues (ATOM records): (download) 
    >1dvmD (D:)
ppsyvahlasdfgvrvfqqvaqaskdrnvvfspygvasvlamlqlttggetqqqiqaamg
fkiddkgmapalrhlykelmgpwnkdeisttdaifvqrdlklvqgfmphffrlfrstvkq
vdfseverarfiindwvkthtkgmishllgtgavqqltrlvlvnalyfngqwktpfpdss
thrrlfhksdgstvsvpmmaqtnkfnytefttpdghyydilelpyhgdtlsmfiaapyek
evplsaltnilsaqlishwkgnmtrlprllvlpkfsletevdlrkplenlgmtdmfrqfq
adftslsdqeplhvalalqkvkievnesgtstavivsarmapeeiiidrpflfvvrhnpt
gtvlfmgqvmep