PDB entry 1dtw

View 1dtw on RCSB PDB site
Description: human branched-chain alpha-keto acid dehydrogenase
Class: oxidoreductase
Keywords: ThDP-binding fold, BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE, OXIDOREDUCTASE
Deposited on 2000-01-13, released 2000-03-27
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-11-16, with a file datestamp of 2011-11-11.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.224
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: branched-chain alpha-keto acid dehydrogenase alpha subunit
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1dtwa_
  • Chain 'B':
    Compound: branched-chain alpha-keto acid dehydrogenase beta subunit
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1dtwb1, d1dtwb2
  • Heterogens: MG, K, TDP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1dtwA (A:)
sslddkpqfpgasaefidklefiqpnvisgipiyrvmdrqgqiinpsedphlpkekvlkl
yksmtllntmdrilyesqrqgrisfymtnygeegthvgsaaaldntdlvfgqyreagvlm
yrdyplelfmaqcygnisdlgkgrqmpvhygckerhfvtissplatqipqavgaayaakr
ananrvvicyfgegaasegdahagfnfaatlecpiiffcrnngyaistptseqyrgdgia
argpgygimsirvdgndvfavynatkearrravaenqpflieamtyrighhstsddssay
rsvdevnywdkqdhpisrlrhyllsqgwwdeeqekawrkqsrrkvmeafeqaerkpkpnp
nllfsdvyqempaqlrkqqeslarhlqtygehypldhfdk

    Sequence, based on observed residues (ATOM records): (download) 
    >1dtwA (A:)
pqfpgasaefidklefiqpnvisgipiyrvmdrqgqiinpsedphlpkekvlklyksmtl
lntmdrilyesqrqgrisfymtnygeegthvgsaaaldntdlvfgqyreagvlmyrdypl
elfmaqcygnisdlgkgrqmpvhygckerhfvtissplatqipqavgaayaakrananrv
vicyfgegaasegdahagfnfaatlecpiiffcrnngyaistptseqyrgdgiaargpgy
gimsirvdgndvfavynatkearrravaenqpflieamtyrighhstsddssayrhpisr
lrhyllsqgwwdeeqekawrkqsrrkvmeafeqaerkpkpnpnllfsdvyqempaqlrkq
qeslarhlqtygehypldhfdk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1dtwB (B:)
vahftfqpdpepreygqtqkmnlfqsvtsaldnslakdptavifgedvafggvfrctvgl
rdkygkdrvfntplceqgivgfgigiavtgataiaeiqfadyifpafdqivneaakyryr
sgdlfncgsltirspwgcvghgalyhsqspeaffahcpgikvviprspfqakglllscie
dknpciffepkilyraaaeevpiepyniplsqaeviqegsdvtlvawgtqvhvirevasm
akeklgvscevidlrtiipwdvdticksviktgrllisheapltggfaseisstvqeecf
lnleapisrvcgydtpfphifepfyipdkwkcydalrkminy

    Sequence, based on observed residues (ATOM records): (download) 
    >1dtwB (B:)
qtqkmnlfqsvtsaldnslakdptavifgedvafggvfrctvglrdkygkdrvfntplce
qgivgfgigiavtgataiaeiqfadyifpafdqivneaakyryrsgdlfncgsltirspw
gcvghgalyhsqspeaffahcpgikvviprspfqakglllsciedknpciffepkilyra
aaeevpiepyniplsqaeviqegsdvtlvawgtqvhvirevasmakeklgvscevidlrt
iipwdvdticksviktgrllisheapltggfaseisstvqeecflnleapisrvcgydtp
fphifepfyipdkwkcydalrkminy