PDB entry 1dtw

View 1dtw on RCSB PDB site
Description: human branched-chain alpha-keto acid dehydrogenase
Class: oxidoreductase
Keywords: ThDP-binding fold, BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE, OXIDOREDUCTASE
Deposited on 2000-01-13, released 2000-03-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-31, with a file datestamp of 2018-01-26.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: branched-chain alpha-keto acid dehydrogenase alpha subunit
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1dtwa_
  • Chain 'B':
    Compound: branched-chain alpha-keto acid dehydrogenase beta subunit
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1dtwb1, d1dtwb2
  • Heterogens: MG, K, TDP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1dtwA (A:)
    sslddkpqfpgasaefidklefiqpnvisgipiyrvmdrqgqiinpsedphlpkekvlkl
    yksmtllntmdrilyesqrqgrisfymtnygeegthvgsaaaldntdlvfgqyreagvlm
    yrdyplelfmaqcygnisdlgkgrqmpvhygckerhfvtissplatqipqavgaayaakr
    ananrvvicyfgegaasegdahagfnfaatlecpiiffcrnngyaistptseqyrgdgia
    argpgygimsirvdgndvfavynatkearrravaenqpflieamtyrighhstsddssay
    rsvdevnywdkqdhpisrlrhyllsqgwwdeeqekawrkqsrrkvmeafeqaerkpkpnp
    nllfsdvyqempaqlrkqqeslarhlqtygehypldhfdk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1dtwA (A:)
    pqfpgasaefidklefiqpnvisgipiyrvmdrqgqiinpsedphlpkekvlklyksmtl
    lntmdrilyesqrqgrisfymtnygeegthvgsaaaldntdlvfgqyreagvlmyrdypl
    elfmaqcygnisdlgkgrqmpvhygckerhfvtissplatqipqavgaayaakrananrv
    vicyfgegaasegdahagfnfaatlecpiiffcrnngyaistptseqyrgdgiaargpgy
    gimsirvdgndvfavynatkearrravaenqpflieamtyrighhstsddssayrhpisr
    lrhyllsqgwwdeeqekawrkqsrrkvmeafeqaerkpkpnpnllfsdvyqempaqlrkq
    qeslarhlqtygehypldhfdk
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1dtwB (B:)
    vahftfqpdpepreygqtqkmnlfqsvtsaldnslakdptavifgedvafggvfrctvgl
    rdkygkdrvfntplceqgivgfgigiavtgataiaeiqfadyifpafdqivneaakyryr
    sgdlfncgsltirspwgcvghgalyhsqspeaffahcpgikvviprspfqakglllscie
    dknpciffepkilyraaaeevpiepyniplsqaeviqegsdvtlvawgtqvhvirevasm
    akeklgvscevidlrtiipwdvdticksviktgrllisheapltggfaseisstvqeecf
    lnleapisrvcgydtpfphifepfyipdkwkcydalrkminy
    

    Sequence, based on observed residues (ATOM records): (download)
    >1dtwB (B:)
    qtqkmnlfqsvtsaldnslakdptavifgedvafggvfrctvglrdkygkdrvfntplce
    qgivgfgigiavtgataiaeiqfadyifpafdqivneaakyryrsgdlfncgsltirspw
    gcvghgalyhsqspeaffahcpgikvviprspfqakglllsciedknpciffepkilyra
    aaeevpiepyniplsqaeviqegsdvtlvawgtqvhvirevasmakeklgvscevidlrt
    iipwdvdticksviktgrllisheapltggfaseisstvqeecflnleapisrvcgydtp
    fphifepfyipdkwkcydalrkminy