PDB entry 1dt6

View 1dt6 on RCSB PDB site
Description: structure of mammalian cytochrome p450 2c5
Class: oxidoreductase
Keywords: membrane protein, progesterone 21-hydroxylase, benzo(a)pyrene hydroxylase, estradiol 2-hydroxylase, P450, CYP2C5, OXIDOREDUCTASE
Deposited on 2000-01-11, released 2000-09-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-24, with a file datestamp of 2019-07-19.
Experiment type: XRAY
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cytochrome p450 2c5
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00179 (Start-468)
      • engineered (78)
      • engineered (183)
      • engineered (187-188)
      • engineered (190-191)
      • engineered (233)
      • c-terminal his tag (469-470)
    Domains in SCOPe 2.08: d1dt6a1, d1dt6a2
  • Heterogens: SM, SO4, HEM

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1dt6A (A:)
makktsskgklppgptpfpiignilqidakdisksltkfsecygpvftvylgmkptvvlh
gyeavkealvdlgeefagrgsvpilekvskglgiafsnaktwkemrrfslmtlrnfgmgk
rsiedriqeearclveelrktnaspcdptfilgcapcnvicsvifhnrfdykdeeflklm
eslhenvellgtpwlqvynnfpalldyfpgihktllknadyiknfimekvkehqklldvn
nprdfidcflikmeqennleftleslviavsdlfgagtettsttlryslllllkhpevaa
rvqeeiervigrhrspcmqdrsrmpytdaviheiqrfidllptnlphavtrdvrfrnyfi
pkgtdiitsltsvlhdekafpnpkvfdpghfldesgnfkksdyfmpfsagkrmcvgegla
rmelflfltsilqnfklqslvepkdlditavvngfvsvppsyqlcfipihhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1dt6A (A:)
ppgptpfpiignilqidakdisksltkfsecygpvftvylgmkptvvlhgyeavkealvd
lgeefagrgsvpilekvskglgiafsnaktwkemrrfslmtlrnfgmgkrsiedriqeea
rclveelrktnaspcdptfilgcapcnvicsvifhnrfdykdeeflklmeslhenvellg
tpldyfpgihktllknadyiknfimekvkehqklldvnnprdfidcflikmeqennleft
leslviavsdlfgagtettsttlryslllllkhpevaarvqeeiervigrhrspcmqdrs
rmpytdaviheiqrfidllptnlphavtrdvrfrnyfipkgtdiitsltsvlhdekafpn
pkvfdpghfldesgnfkksdyfmpfsagkrmcvgeglarmelflfltsilqnfklqslve
pkdlditavvngfvsvppsyqlcfipihh