PDB entry 1dsz

View 1dsz on RCSB PDB site
Description: structure of the rxr/rar DNA-binding domain heterodimer in complex with the retinoic acid response element dr1
Class: transcription/DNA
Keywords: RXR, RAR, nuclear receptor, protein-DNA, retinoic acid, TRANSCRIPTION/DNA COMPLEX
Deposited on 2000-01-10, released 2000-07-10
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.198
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: retinoic acid receptor alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1dsza_
  • Chain 'B':
    Compound: Retinoic acid receptor RXR-alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19793 (1-End)
      • insertion (0)
    Domains in SCOPe 2.07: d1dszb_
  • Chain 'C':
    Compound: DNA (5'-d(*cp*ap*gp*gp*tp*cp*ap*ap*ap*gp*gp*tp*cp*ap*g)-3')
  • Chain 'D':
    Compound: DNA (5'-d(*cp*tp*gp*ap*cp*cp*tp*tp*tp*gp*ap*cp*cp*tp*g)-3')
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1dszA (A:)
priykpcfvcqdkssgyhygvsacegckgffrrsiqknmvytchrdknciinkvtrnrcq
ycrlqkcfevgmskesvrndrnkkkk

    Sequence, based on observed residues (ATOM records): (download) 
    >1dszA (A:)
pcfvcqdkssgyhygvsacegckgffrrsiqknmvytchrdknciinkvtrnrcqycrlq
kcfevgmskesvrnd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1dszB (B:)
gsftkhicaicgdrssgkhygvyscegckgffkrtvrkdltytcrdnkdclidkrqrnrc
qycryqkclamgmkreavqeerqrg

    Sequence, based on observed residues (ATOM records): (download) 
    >1dszB (B:)
gsftkhicaicgdrssgkhygvyscegckgffkrtvrkdltytcrdnkdclidkrqrnrc
qycryqkclamgmkreavqeerqr

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.