PDB entry 1dm4
View 1dm4 on RCSB PDB site
Description: ser195ala mutant of human thrombin complexed with fibrinopeptide a (7-16)
Class: hydrolase
Keywords: mutant thrombin, residual catalytic activity, fibrinopeptide a, hydrolase
Deposited on
1999-12-13, released
2000-01-19
The last revision prior to the SCOPe 2.08 freeze date was dated
2018-03-14, with a file datestamp of
2018-03-09.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.19
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: protein (alpha thrombin:light chain)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1dm4.1 - Chain 'B':
Compound: protein (mutant alpha thrombin:heavy chain)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P00734 (Start-259)
- engineered mutation (205)
Domains in SCOPe 2.08: d1dm4.1 - Chain 'C':
Compound: protein (fibrinopeptide)
Database cross-references and differences (RAF-indexed):
- Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1dm4A (A:)
tfgsgeadcglrplfekksledkterellesyidg
Sequence, based on observed residues (ATOM records): (download)
>1dm4A (A:)
tfgsgeadcglrplfekksledkterellesyi
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1dm4B (B:)
rivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendl
lvrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvc
lpdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstri
ritdnmfcagykpdegkrgdacegdaggpfvmkspfnnrwyqmgivswgegcdrdgkygf
ythvfrlkkwiqkvidqfge
Sequence, based on observed residues (ATOM records): (download)
>1dm4B (B:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketgqpsvlqvvnlpiverpvckdstriritdnmfc
agykpdegkrgdacegdaggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrlk
kwiqkvidqfge
- Chain 'C':
No sequence available.