PDB entry 1dkv

View 1dkv on RCSB PDB site
Description: the crystal structure of calcium-free human m-calpain
Class: hydrolase
Keywords: m-calpain, calcium, papain-like
Deposited on 1999-12-08, released 2000-01-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2001-12-07, with a file datestamp of 2007-04-25.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.206
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: m-calpain
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04632 (Start-699)
      • conflict (210)
      • conflict (295)
      • conflict (445)
    Domains in SCOPe 2.08: d1dkva4, d1dkva5, d1dkva6
  • Chain 'B':
    Compound: calpain
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • GB NP_001740 (0-183)
    Domains in SCOPe 2.08: d1dkvb_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1dkvA (A:)
magiaaklakdreaaeglgsheraikylnqdyealrnecleagtlfqdpsfpaipsalgf
kelgpyssktrgmrwkrpteicadpqfiiggatrtdicqgalgdcwllaaiasltlneei
larvvplnqsfqenyagifhfqfwqygewvevvvddrlptkdgellfvhsaegsefwsal
lekayakingcyealsggattegfedftgglaewyelkkpppnlfkiiqkalqkgsllgc
siditsaadseaitfqklvkghaysvtgaeevesngslqklirirnpwgevewtgawndn
cpswntidpeererltrrhedgefwmsfsdflrhysrleicnltpdtltsdtykkwkltk
mdgnwrrgstaggcrnypntfwmnpqylikleeededeedgesgctflvgliqkhrrrqr
kmgedmhtigfgiyevpeelsgqtnlhlsknffltnrarersdtfinlrevlnrfklppg
eyilvpstfepnkdgdfcirvfsekkadyqavddeieanleefdiseddiddgvrrlfaq
lagedaeisafelqtilrrvlakrqdiksdgfsietckimvdmldsdgsgklglkefyil
wtkiqkyqkiyreidvdrsgtmnsyemrkaleeagfkmpcqlhqvivarfaddqliidfd
nfvrclvrletlfkifkqldpentgtieldliswlcfsvl

    Sequence, based on observed residues (ATOM records): (download) 
    >1dkvA (A:)
agiaaklakdreaaeglgsheraikylnqdyealrnecleagtlfqdpsfpaipsalgfk
elgpyssktrgmrwkrpteicadpqfiiggatrtdicqgalgdcwllaaiasltlneeil
arvvplnqsfqenyagifhfqfwqygewvevvvddrlptkdgellfvhsaegsefwsall
ekayakingcyealsggattegfedftgglaewyelkkpppnlfkiiqkalqkgsllgcs
iditsaadseaitfqklvkghaysvtgaeevesngslqklirirnpwgevewtgawndnc
pswntidpeererltrrhedgefwmsfsdflrhysrleicnltpdtltsdtykkwkltkm
dgnwrrgstaggcrnypntfwmnpqylikleeededeedgesgctflvgliqkhrrrqrk
mgedmhtigfgiyevpeelsgqtnlhlsknffltnrarersdtfinlrevlnrfklppge
yilvpstfepnkdgdfcirvfsekkadyqavddeieanleefdiseddiddgvrrlfaql
agedaeisafelqtilrrvlakrqdiksdgfsietckimvdmldsdgsgklglkefyilw
tkiqkyqkiyreidvdrsgtmnsyemrkaleeagfkmpcqlhqvivarfaddqliidfdn
fvrclvrletlfkifkqldpentgtieldliswlcfsvl

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1dkvB (B:)
thysnieaneseevrqfrrlfaqlagddmevsatelmnilnkvvtrhpdlktdgfgidtc
rsmvavmdsdttgklgfeefkylwnnikrwqaiykqfdtdrsgticsselpgafeaagfh
lnehlynmiirrysdesgnmdfdnfisclvrldamfrafksldkdgtgqiqvniqewlql
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