PDB entry 1dia

View 1dia on RCSB PDB site
Description: human methylenetetrahydrofolate dehydrogenase / cyclohydrolase complexed with nadp and inhibitor ly249543
Deposited on 1999-11-29, released 2000-07-05
The last revision prior to the SCOP 1.67 freeze date was dated 2000-07-05, with a file datestamp of 2000-07-05.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.227
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1diaA (A:)
mapaeilngkeisaqirarlknqvtqlkeqvpgftprlailqvgnrddsnlyinvklkaa
eeigikathiklprtttesevmkyitslnedstvhgflvqlpldsensinteevinaiap
ekdvdgltsinagrlargdlndcfipctpkgcleliketgvpiagrhavvvgrskivgap
mhdlllwnnatvttchsktahldeevnkgdilvvatgqpemvkgewikpgaividcginy
vpddkkpngrkvvgdvaydeakerasfitpvpggvgpmtvamlmqstvesakrflekfkp
gkwmiq

    Sequence, based on observed residues (ATOM records): (download) 
    >1diaA (A:)
apaeilngkeisaqirarlknqvtqlkeqvpgftprlailqvgnrddsnlyinvklkaae
eigikathiklprtttesevmkyitslnedstvhgflvqlpldsensinteevinaiape
kdvdgltsinagrlargdlndcfipctpkgcleliketgvpiagrhavvvgrskivgapm
hdlllwnnatvttchsktahldeevnkgdilvvatgqpemvkgewikpgaividcginyk
vvgdvaydeakerasfitpvpggvgpmtvamlmqstvesakrfle

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1diaB (B:)
mapaeilngkeisaqirarlknqvtqlkeqvpgftprlailqvgnrddsnlyinvklkaa
eeigikathiklprtttesevmkyitslnedstvhgflvqlpldsensinteevinaiap
ekdvdgltsinagrlargdlndcfipctpkgcleliketgvpiagrhavvvgrskivgap
mhdlllwnnatvttchsktahldeevnkgdilvvatgqpemvkgewikpgaividcginy
vpddkkpngrkvvgdvaydeakerasfitpvpggvgpmtvamlmqstvesakrflekfkp
gkwmiq

    Sequence, based on observed residues (ATOM records): (download) 
    >1diaB (B:)
apaeilngkeisaqirarlknqvtqlkeqvpgftprlailqvgnrddsnlyinvklkaae
eigikathiklprtttesevmkyitslnedstvhgflvqlpldsensinteevinaiape
kdvdgltsinagrlargdlndcfipctpkgcleliketgvpiagrhavvvgrskivgapm
hdlllwnnatvttchsktahldeevnkgdilvvatgqpemvkgewikpgaividcginyv
pddkkpngrkvvgdvaydeakerasfitpvpggvgpmtvamlmqstvesakrfle