PDB entry 1dhf

View 1dhf on RCSB PDB site
Description: crystal structures of recombinant human dihydrofolate reductase complexed with folate and 5-deazofolate
Class: oxido-reductase
Keywords: oxido-reductase
Deposited on 1989-10-25, released 1990-07-15
The last revision prior to the SCOP 1.73 freeze date was dated 2003-04-01, with a file datestamp of 2007-06-04.
Experiment type: -
Resolution: 2.3 Å
R-factor: 0.176
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydrofolate reductase
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1dhfa_
  • Chain 'B':
    Compound: dihydrofolate reductase
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1dhfb_
  • Heterogens: FOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1dhfA (A:)
vgslncivavsqnmgigkngdlpwpplrnefryfqrmtttssvegkqnlvimgkktwfsi
peknrplkgrinlvlsrelkeppqgahflsrslddalklteqpelankvdmvwivggssv
ykeamnhpghlklfvtrimqdfesdtffpeidlekykllpeypgvlsdvqeekgikykfe
vyeknd

    Sequence, based on observed residues (ATOM records): (download) 
    >1dhfA (A:)
lncivavsqnmgigkngdlpwpplrnefryfqrmtttssvegkqnlvimgkktwfsipek
nrplkgrinlvlsrelkeppqgahflsrslddalklteqpelankvdmvwivggssvyke
amnhpghlklfvtrimqdfesdtffpeidlekykllpeypgvlsdvqeekgikykfevye
kn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1dhfB (B:)
vgslncivavsqnmgigkngdlpwpplrnefryfqrmtttssvegkqnlvimgkktwfsi
peknrplkgrinlvlsrelkeppqgahflsrslddalklteqpelankvdmvwivggssv
ykeamnhpghlklfvtrimqdfesdtffpeidlekykllpeypgvlsdvqeekgikykfe
vyeknd

    Sequence, based on observed residues (ATOM records): (download) 
    >1dhfB (B:)
lncivavsqnmgigkngdlpwpplrnefryfqrmtttssvegkqnlvimgkktwfsipek
nrplkgrinlvlsrelkeppqgahflsrslddalklteqpelankvdmvwivggssvyke
amnhpghlklfvtrimqdfesdtffpeidlekykllpeypgvlsdvqeekgikykfevye
kn