PDB entry 1dgk

View 1dgk on RCSB PDB site
Description: mutant monomer of recombinant human hexokinase type I with glucose and ADP in the active site
Class: transferase
Keywords: brain hexokinase, mammalian hexokinase 1, sugar kinase
Deposited on 1999-11-24, released 2000-03-08
The last revision prior to the SCOP 1.75 freeze date was dated 2003-04-01, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.26
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'N':
    Compound: hexokinase type I
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19367
      • engineered (239)
      • engineered (242)
      • engineered (283)
      • engineered (535)
      • conflict (729)
      • conflict (775)
    Domains in SCOP 1.75: d1dgkn1, d1dgkn2, d1dgkn3, d1dgkn4
  • Heterogens: GLC, PO4, ADP, HOH

PDB Chain Sequences:

  • Chain 'N':
    Sequence, based on SEQRES records: (download) 
    >1dgkN (N:)
miaaqllayyftelkddqvkkidkylyamrlsdetlidimtrfrkemknglsrdfnptat
vkmlptfvrsipdgsekgdfialdlggssfrilrvqvnheknqnvhmesevydtpenivh
gsgsqlfdhvaeclgdfmekrkikdkklpvgftfsfpcqqskideailitwtkrfkasgv
egadvvkllnkaikkrgdydanivavvndtvgtmmtcgyddqhcevgliigtgtnacyme
elrhidlvegdegrmcintewgafgddgsledirtefdraidayslnpgkqlfekmvsgm
ylgelvrlilvkmakegllfegritpelltrgkfntsdvsaieknkeglhnakeiltrlg
vepsdddcvsvqhvctivsfrsanlvaatlgailnrlrdnkgtprlrttvgvdgslykth
pqysrrfhktlrrlvpdsdvrfllsesgsgkgaamvtavayrlaeqhrqieetlahfhlt
kdmllevkkrmraemelglrkqthnnavvkmlpsfvrrtpdgtengdflaldlgganfrv
llvkirsgkkrtvemhnkiyaipieimqgtgeelfdhivscisdfldymgikgprmplgf
tfsfpcqqtsldagilitwtkgfkatdcvghdvvtllrdaikrreefdldvvavvndtvg
tmmtcayeeptcevglivgtgsnacymeemknvemvegdqgqmcinmewgafgdngcldd
irthydrlvdeyslnagkqryekmisgmylgeivrnilidftkkgflfrgqisetlktrg
ifetkflsqiesdrlallqvrailqqlglnstcddsilvktvcgvvsrraaqlcgagmaa
vvdkirenrgldrlnvtvgvdgtlyklhphfsrimhqtvkelspkcnvsfllsedgsgkg
aalitavgvrlrteass

    Sequence, based on observed residues (ATOM records): (download) 
    >1dgkN (N:)
ddqvkkidkylyamrlsdetlidimtrfrkemknglsrdfnptatvkmlptfvrsipdgs
ekgdfialdlggssfrilrvqvnheknqnvhmesevydtpenivhgsgsqlfdhvaeclg
dfmekrkikdkklpvgftfsfpcqqskideailitwtkrfkasgvegadvvkllnkaikk
rgdydanivavvndtvgtmmtcgyddqhcevgliigtgtnacymeelrhidlvegdegrm
cintewgafgddgsledirtefdraidayslnpgkqlfekmvsgmylgelvrlilvkmak
egllfegritpelltrgkfntsdvsaieknkeglhnakeiltrlgvepsdddcvsvqhvc
tivsfrsanlvaatlgailnrlrdnkgtprlrttvgvdgslykthpqysrrfhktlrrlv
pdsdvrfllsesgsgkgaamvtavayrlaeqhrqieetlahfhltkdmllevkkrmraem
elglrkqthnnavvkmlpsfvrrtpdgtengdflaldlgganfrvllvkirsgkkrtvem
hnkiyaipieimqgtgeelfdhivscisdfldymgikgprmplgftfsfpcqqtsldagi
litwtkgfkatdcvghdvvtllrdaikrreefdldvvavvndtvgtmmtcayeeptcevg
livgtgsnacymeemknvemvegdqgqmcinmewgafgdngclddirthydrlvdeysln
agkqryekmisgmylgeivrnilidftkkgflfrgqisetlktrgifetkflsqiesdrl
allqvrailqqlglnstcddsilvktvcgvvsrraaqlcgagmaavvdkirenrgldrln
vtvgvdgtlyklhphfsrimhqtvkelspkcnvsfllsedgsgkgaalitavgvrlrt