PDB entry 1df7
View 1df7 on RCSB PDB site
Description: dihydrofolate reductase of mycobacterium tuberculosis complexed with nadph and methotrexate
Class: oxidoreductase
Keywords: dihydrofolate reductase, structure-based inhibitor design, folateanalogs, rossmann fold, nicotinamide adenine dinucleotide, methotrexate, tuberculosis, oxidoreductase
Deposited on
1999-11-17, released
2000-03-09
The last revision prior to the SCOPe 2.08 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-25.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.187
AEROSPACI score: 0.53
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: dihydrofolate reductase
Species: Mycobacterium tuberculosis [TaxId:1773]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1df7a_ - Heterogens: SO4, NDP, MTX, GOL, HOH