PDB entry 1de7

View 1de7 on RCSB PDB site
Description: interaction of factor xiii activation peptide with alpha-thrombin: crystal structure of the enzyme-substrate complex
Class: hydrolase/hydrolase substrate
Keywords: ENZYME-SUBSTRATE COMPLEX, ALPHA-THROMBIN, FACTOR XIII ACTIVATION PEPTIDE, HYDROLASE/PEPTIDE, BLOOD CLOTTING, HYDROLASE-HYDROLASE SUBSTRATE complex
Deposited on 1999-11-13, released 2000-12-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.194
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: factor xiii activation peptide (28-37)
    Database cross-references and differences (RAF-indexed):
    • PDB 1DE7 (0-10)
  • Chain 'B':
    Compound: factor xiii activation peptide (28-37)
    Database cross-references and differences (RAF-indexed):
    • PDB 1DE7 (0-10)
  • Chain 'H':
    Compound: alpha-thrombin (heavy chain)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1de7.1
  • Chain 'J':
    Compound: alpha-thrombin (light chain)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1de7.2
  • Chain 'K':
    Compound: alpha-thrombin (heavy chain)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1de7.2
  • Chain 'L':
    Compound: alpha-thrombin (light chain)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1de7.1
  • Heterogens: NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >1de7H (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge

    Sequence, based on observed residues (ATOM records): (download) 
    >1de7H (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketgqpsvlqvvnlpiverpvckdstriritdnmfc
agykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrlk
kwiqkvidq

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >1de7J (J:)
tfgsgeadcglrplfekksledkterellesyidgr

    Sequence, based on observed residues (ATOM records): (download) 
    >1de7J (J:)
dcglrplfekksledkterellesyi

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >1de7K (K:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge

    Sequence, based on observed residues (ATOM records): (download) 
    >1de7K (K:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketgqpsvlqvvnlpiverpvckdstriritdnmfc
agykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrlk
kwiqkvidqfg

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >1de7L (L:)
tfgsgeadcglrplfekksledkterellesyidgr

    Sequence, based on observed residues (ATOM records): (download) 
    >1de7L (L:)
eadcglrplfekksledkterellesyi