PDB entry 1ddr

View 1ddr on RCSB PDB site
Description: molecule: dihydrofolate reductase (e.c.1.5.1.3) complexed with methotrexate and urea
Class: oxido-reductase
Keywords: oxido-reductase
Deposited on 1995-06-29, released 1995-10-15
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.45 Å
R-factor: 0.156
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydrofolate reductase
    Species: Escherichia coli [TaxId:37762]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1ddra_
  • Chain 'B':
    Compound: dihydrofolate reductase
    Species: Escherichia coli [TaxId:37762]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1ddrb_
  • Heterogens: CL, CA, MTX, URE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1ddrA (A:)
    misliaalavdrvigmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkni
    ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
    gdthfpdyepddwesvfsefhdadaqnshsycfeilerr
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1ddrB (B:)
    misliaalavdrvigmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkni
    ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
    gdthfpdyepddwesvfsefhdadaqnshsycfeilerr