PDB entry 1dan

View 1dan on RCSB PDB site
Description: complex of active site inhibited human blood coagulation factor viia with human recombinant soluble tissue factor
Class: complex(serine protease/cofactor/ligand)
Keywords: blood coagulation, serine protease, complex, co-factor, receptor enzyme, inhibitor, gla, egf, complex (serine protease/cofactor/ligand)
Deposited on 1997-03-05, released 1997-09-04
The last revision prior to the SCOP 1.73 freeze date was dated 2003-04-01, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.187
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'C':
    Compound: d-phe-phe-arg-chloromethylketone (dffrcmk) with chloromethylketone replaced by a methylene group
  • Chain 'H':
    Compound: blood coagulation factor viia
    Species: HOMO SAPIENS
    Domains in SCOP 1.73: d1danh_
  • Chain 'L':
    Compound: blood coagulation factor viia
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08709 (15-End)
      • modified residue (5-6)
      • modified residue (13)
      • modified residue (15)
      • modified residue (18-19)
      • modified residue (24-25)
      • modified residue (28)
      • modified residue (34)
    Domains in SCOP 1.73: d1danl1, d1danl2, d1danl3
  • Chain 'T':
    Compound: soluble tissue factor
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1dan.1
  • Chain 'U':
    Compound: soluble tissue factor
    Species: HOMO SAPIENS
    Domains in SCOP 1.73: d1dan.1, d1danu1
  • Heterogens: BGC, FUC, CA, CAC, CL, CH2, HOH

PDB Chain Sequences:

  • Chain 'C':
    No sequence available.

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1danH (H:)
    ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
    lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
    lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
    sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
    seprpgvllrapfp
    

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >1danL (L:)
    anafleelrpgslereckeeqcsfeeareifkdaertklfwisysdgdqcasspcqnggs
    ckdqlqsyicfclpafegrncethkddqlicvnenggceqycsdhtgtkrscrchegysl
    ladgvsctptveypcgkipilekrnaskpqgr
    

    Sequence, based on observed residues (ATOM records): (download)
    >1danL (L:)
    anafleelrpgslereckeeqcsfeeareifkdaertklfwisysdgdqcasspcqnggs
    ckdqlqsyicfclpafegrncethkddqlicvnenggceqycsdhtgtkrscrchegysl
    ladgvsctptveypcgkipile
    

  • Chain 'T':
    Sequence, based on SEQRES records: (download)
    >1danT (T:)
    ntvaaynltwkstnfktilewepkpvnqvytvqistksgdwkskcfyttdtecdltdeiv
    kdvkqtylarvfsypagnve
    

    Sequence, based on observed residues (ATOM records): (download)
    >1danT (T:)
    tvaaynltwkstnfktilewepkpvnqvytvqistksgdwkskcfyttdtecdltdeivk
    dvkqtylarvfsypa
    

  • Chain 'U':
    Sequence, based on SEQRES records: (download)
    >1danU (U:)
    geplyenspeftpyletnlgqptiqsfeqvgtkvnvtvedertlvrrnntflslrdvfgk
    dliytlyywkssssgkktaktntneflidvdkgenycfsvqavipsrtvnrkstdspvec
    m
    

    Sequence, based on observed residues (ATOM records): (download)
    >1danU (U:)
    eplyenspeftpyletnlgqptiqsfeqvgtkvnvtvedertlvrrnntflslrdvfgkd
    liytlyywsgkktaktntneflidvdkgenycfsvqavipsrtvnrkstdspvecm