PDB entry 1d6n
View 1d6n on RCSB PDB site
Description: ternary complex structure of human hgprtase, prpp, mg2+, and the inhibitor hpp reveals the involvement of the flexible loop in substrate binding
Class: transferase
Keywords: hgprtase, transferase
Deposited on
1999-10-14, released
1999-12-30
The last revision prior to the SCOPe 2.08 freeze date was dated
2020-07-29, with a file datestamp of
2020-07-04.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.14
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: protein (hypoxanthine-guanine phosphoribosyltransferase)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P00492 (0-213)
- engineered (64)
- conflict (98)
Domains in SCOPe 2.08: d1d6na_ - Chain 'B':
Compound: protein (hypoxanthine-guanine phosphoribosyltransferase)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P00492 (0-213)
- engineered (64)
- conflict (98)
Domains in SCOPe 2.08: d1d6nb_ - Heterogens: MG, PPO, PRP, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1d6nA (A:)
spgvvisddepgydldlfcipnhyaedlervfiphglimdrterlardvmkemgghhiva
lcvlaggykffadlldyikalnrnsdrsipmtvdfirlgsycndqstgdikviggddlst
ltgknvlivediidtgktmqtllslvrqynpkmvkvasllvkrtprsvgykpdfvgfeip
dkfvvgyaldyneyfrdlnhvcvisetgkakyka
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>1d6nB (B:)
spgvvisddepgydldlfcipnhyaedlervfiphglimdrterlardvmkemgghhiva
lcvlaggykffadlldyikalnrnsdrsipmtvdfirlgsycndqstgdikviggddlst
ltgknvlivediidtgktmqtllslvrqynpkmvkvasllvkrtprsvgykpdfvgfeip
dkfvvgyaldyneyfrdlnhvcvisetgkakyka