PDB entry 1d3p
View 1d3p on RCSB PDB site
Description: crystal structure of human aplha-thrombin in complex with benzo[b]thiophene inhibitor 3
Class: hydrolase/hydrolase inhibitor
Keywords: thrombin, benzo[b]thiophene, blood clotting, hydrolase-hydrolase inhibitor complex
Deposited on
1999-09-30, released
2000-10-04
The last revision prior to the SCOPe 2.07 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-08.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.179
AEROSPACI score: 0.42
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: alpha-thrombin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d1d3p.1 - Chain 'B':
Compound: alpha-thrombin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d1d3p.1 - Chain 'H':
Compound: hirugen
Species: Hirudo medicinalis [TaxId:6421]
Database cross-references and differences (RAF-indexed):
- Heterogens: NAG, NA, BT3, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1d3pA (A:)
tfgsgeadcglrplfekksledkterellesyidgr
Sequence, based on observed residues (ATOM records): (download)
>1d3pA (A:)
eadcglrplfekksledkterellesyi
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1d3pB (B:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge
Sequence, based on observed residues (ATOM records): (download)
>1d3pB (B:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketgqpsvlqvvnlpiverpvckdstriritdnmfc
agykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrlk
kwiqkvidqf
- Chain 'H':
No sequence available.