PDB entry 1cza

View 1cza on RCSB PDB site
Description: mutant monomer of recombinant human hexokinase type I complexed with glucose, glucose-6-phosphate, and ADP
Class: transferase
Keywords: structurally homologous domains, transferase
Deposited on 1999-09-01, released 2000-03-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'N':
    Compound: hexokinase type I
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19367
      • engineered (279)
      • engineered (282-283)
      • see remark 999 (729)
      • see remark 999 (775)
    Domains in SCOPe 2.08: d1czan1, d1czan2, d1czan3, d1czan4
  • Heterogens: GLC, G6P, ADP, HOH

PDB Chain Sequences:

  • Chain 'N':
    Sequence, based on SEQRES records: (download) 
    >1czaN (N:)
miaaqllayyftelkddqvkkidkylyamrlsdetlidimtrfrkemknglsrdfnptat
vkmlptfvrsipdgsekgdfialdlggssfrilrvqvnheknqnvhmesevydtpenivh
gsgsqlfdhvaeclgdfmekrkikdkklpvgftfsfpcqqskideailitwtkrfkasgv
egadvvkllnkaikkrgdydanivavvndtvgtmmtcgyddqhcevgliigtgtnacyme
elrhidlvegdegrmcintewgafgddgsledirtefdraidayslnpgkqlfekmvsgm
ylgelvrlilvkmakegllfegritpelltrgkfntsdvsaieknkeglhnakeiltrlg
vepsdddcvsvqhvctivsfrsanlvaatlgailnrlrdnkgtprlrttvgvdgslykth
pqysrrfhktlrrlvpdsdvrfllsesgsgkgaamvtavayrlaeqhrqieetlahfhlt
kdmllevkkrmraemelglrkqthnnavvkmlpsfvrrtpdgtengdflaldlggtnfrv
llvkirsgkkrtvemhnkiyaipieimqgtgeelfdhivscisdfldymgikgprmplgf
tfsfpcqqtsldagilitwtkgfkatdcvghdvvtllrdaikrreefdldvvavvndtvg
tmmtcayeeptcevglivgtgsnacymeemknvemvegdqgqmcinmewgafgdngcldd
irthydrlvdeyslnagkqryekmisgmylgeivrnilidftkkgflfrgqisetlktrg
ifetkflsqiesdrlallqvrailqqlglnstcddsilvktvcgvvsrraaqlcgagmaa
vvdkirenrgldrlnvtvgvdgtlyklhphfsrimhqtvkelspkcnvsfllsedgsgkg
aalitavgvrlrteass

    Sequence, based on observed residues (ATOM records): (download) 
    >1czaN (N:)
ddqvkkidkylyamrlsdetlidimtrfrkemknglsrdfnptatvkmlptfvrsipdgs
ekgdfialdlggssfrilrvqvnheknqnvhmesevydtpenivhgsgsqlfdhvaeclg
dfmekrkikdkklpvgftfsfpcqqskideailitwtkrfkasgvegadvvkllnkaikk
rgdydanivavvndtvgtmmtcgyddqhcevgliigtgtnacymeelrhidlvegdegrm
cintewgafgddgsledirtefdraidayslnpgkqlfekmvsgmylgelvrlilvkmak
egllfegritpelltrgkfntsdvsaieknkeglhnakeiltrlgvepsdddcvsvqhvc
tivsfrsanlvaatlgailnrlrdnkgtprlrttvgvdgslykthpqysrrfhktlrrlv
pdsdvrfllsesgsgkgaamvtavayrlaeqhrqieetlahfhltkdmllevkkrmraem
elglrkqthnnavvkmlpsfvrrtpdgtengdflaldlggtnfrvllvkirsgkkrtvem
hnkiyaipieimqgtgeelfdhivscisdfldymgikgprmplgftfsfpcqqtsldagi
litwtkgfkatdcvghdvvtllrdaikrreefdldvvavvndtvgtmmtcayeeptcevg
livgtgsnacymeemknvemvegdqgqmcinmewgafgdngclddirthydrlvdeysln
agkqryekmisgmylgeivrnilidftkkgflfrgqisetlktrgifetkflsqiesdrl
allqvrailqqlglnstcddsilvktvcgvvsrraaqlcgagmaavvdkirenrgldrln
vtvgvdgtlyklhphfsrimhqtvkelspkcnvsfllsedgsgkgaalitavgvrlrt