PDB entry 1cy8

View 1cy8 on RCSB PDB site
Description: complex of e.coli DNA topoisomerase I with 5'-thymidine monophosphate and 3'-thymidine monophosphate
Class: isomerase
Keywords: DNA topoisomerase, relaxing enzyme, isomerase
Deposited on 1999-08-31, released 2000-03-08
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.45 Å
R-factor: 0.225
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA topoisomerase I
    Species: Escherichia coli [TaxId:83333]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1cy8a_
  • Heterogens: PO4, T3P, TMP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1cy8A (A:)
    gsmgkalvivespakaktinkylgsdyvvkssvghirdlptsgsaakksadststktakk
    pkkdergalvnrmgvdpwhnweahyevlpgkekvvselkqlaekadhiylatdldregea
    iawhlreviggddarysrvvfneitknairqafnkpgelnidrvnaqqarrfmdrvvgym
    vspllwkkiarglsagrvqsvavrlvverereikafvpeefwevdastttpsgealalqv
    thqndkpfrpvnkeqtqaavsllekarysvleredkpttskpgapfitstlqqaastrlg
    fgvkktmmmaqrlyeagyitymrtdstnlsqdavnmvrgyisdnfgkkylpespnqyask
    ensqeaheairpsdvnvmaeslkdmeadaqklyqliwrqfvacqmtpakydsttltvgag
    dfrlkargrilrfdgwtkvmpalrkgdedrilpavnkgdaltlveltpaqhftkpparfs
    easlvkelekrgigrpstyasiistiqdrgyvrvenrrfyaekmgeivtdrleenfrelm
    nydftaqmensldqvanheaewkavldhffsdftqqldkaekdpeeggmrpnqmvltsi
    

    Sequence, based on observed residues (ATOM records): (download)
    >1cy8A (A:)
    gkalvivespakaktinkylgsdyvvkssvghirdlpdergalvnrmgvdpwhnweahye
    vlpgkekvvselkqlaekadhiylatdldregeaiawhlreviggddarysrvvfneitk
    nairqafnkpgelnidrvnaqqarrfmdrvvgymvspllwkkiarglsagrvqsvavrlv
    verereikafvpeefwevdastttpsgealalqvthqndkpfrpvnkeqtqaavslleka
    rysvleredkpttskpgapfitstlqqaastrlgfgvkktmmmaqrlyeagyitymrtds
    tnlsqdavnmvrgyisdnfgkkylpespnqyaheairpsdvnvmaeslkdmeadaqklyq
    liwrqfvacqmtpakydsttltvgagdfrlkargrilrfdgwtkvmpalrkgdedrilpa
    vnkgdaltlveltpaqhftkpparfseaslvkelekrgigrpstyasiistiqdrgyvrv
    enrrfyaekmgeivtdrleenfrelmnydftaqmensldqvanheaewkavldhffsdft
    qqldkaekdpeeggmrpnqmvlt