PDB entry 1cx2

View 1cx2 on RCSB PDB site
Description: cyclooxygenase-2 (prostaglandin synthase-2) complexed with a selective inhibitor, sc-558
Deposited on 1996-12-17, released 1997-12-24
The last revision prior to the SCOP 1.69 freeze date was dated 1997-12-24, with a file datestamp of 1997-12-24.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.216
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1cx2A (A:)
anpccsnpcqnrgecmstgfdqykcdctrtgfygencttpefltriklllkptpntvhyi
lthfkgvwnivnnipflrslimkyvltsrsylidspptynvhygyksweafsnlsyytra
lppvaddcptpmgvkgnkelpdskevlekvllrrefipdpqgsnmmfaffaqhfthqffk
tdhkrgpgftrglghgvdlnhiygetldrqhklrlfkdgklkyqviggevypptvkdtqv
emiypphipenlqfavgqevfglvpglmmyatiwlrehqrvcdilkqehpewgdeqlfqt
skliligetikiviedyvqhlsgyhfklkfdpellfnqqfqyqnriasefntlyhwhpll
pdtfniedqeysfkqflynnsillehgltqfvesftrqiagrvaggrnvpiavqavakas
idqsremkyqslneyrkrfslkpytsfeeltgekemaaelkalysdidvmelypallvek
prpdaifgetmvelgapfslkglmgnpicspqywkpstfggevgfkiintasiqslicnn
vkgcpftsfnvqdpqptktatinasashsrlddinptvlikrrstel

    Sequence, based on observed residues (ATOM records): (download) 
    >1cx2A (A:)
anpccsnpcqnrgecmstgfdqykcdctrtgfygencttpefltriklllkptpntvhyi
lthfkgvwnivnnipflrslimkyvltsrsylidspptynvhygyksweafsnlsyytra
lppvaddcptpmgvkgnkelpdskevlekvllrrefipdpqgsnmmfaffaqhfthqffk
tdhkrgpgftrglghgvdlnhiygetldrqhklrlfkdgklkyqviggevypptvkdtqv
emiypphipenlqfavgqevfglvpglmmyatiwlrehqrvcdilkqehpewgdeqlfqt
skliligetikiviedyvqhlsgyhfklkfdpellfnqqfqyqnriasefntlyhwhpll
pdtfniedqeysfkqflynnsillehgltqfvesftrqiagrvaggrnvpiavqavakas
idqsremkyqslneyrkrfslkpytsfeeltgekemaaelkalysdidvmelypallvek
prpdaifgetmvelgapfslkglmgnpicspqywkpstfggevgfkiintasiqslicnn
vkgcpftsfnvq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1cx2B (B:)
anpccsnpcqnrgecmstgfdqykcdctrtgfygencttpefltriklllkptpntvhyi
lthfkgvwnivnnipflrslimkyvltsrsylidspptynvhygyksweafsnlsyytra
lppvaddcptpmgvkgnkelpdskevlekvllrrefipdpqgsnmmfaffaqhfthqffk
tdhkrgpgftrglghgvdlnhiygetldrqhklrlfkdgklkyqviggevypptvkdtqv
emiypphipenlqfavgqevfglvpglmmyatiwlrehqrvcdilkqehpewgdeqlfqt
skliligetikiviedyvqhlsgyhfklkfdpellfnqqfqyqnriasefntlyhwhpll
pdtfniedqeysfkqflynnsillehgltqfvesftrqiagrvaggrnvpiavqavakas
idqsremkyqslneyrkrfslkpytsfeeltgekemaaelkalysdidvmelypallvek
prpdaifgetmvelgapfslkglmgnpicspqywkpstfggevgfkiintasiqslicnn
vkgcpftsfnvqdpqptktatinasashsrlddinptvlikrrstel

    Sequence, based on observed residues (ATOM records): (download) 
    >1cx2B (B:)
anpccsnpcqnrgecmstgfdqykcdctrtgfygencttpefltriklllkptpntvhyi
lthfkgvwnivnnipflrslimkyvltsrsylidspptynvhygyksweafsnlsyytra
lppvaddcptpmgvkgnkelpdskevlekvllrrefipdpqgsnmmfaffaqhfthqffk
tdhkrgpgftrglghgvdlnhiygetldrqhklrlfkdgklkyqviggevypptvkdtqv
emiypphipenlqfavgqevfglvpglmmyatiwlrehqrvcdilkqehpewgdeqlfqt
skliligetikiviedyvqhlsgyhfklkfdpellfnqqfqyqnriasefntlyhwhpll
pdtfniedqeysfkqflynnsillehgltqfvesftrqiagrvaggrnvpiavqavakas
idqsremkyqslneyrkrfslkpytsfeeltgekemaaelkalysdidvmelypallvek
prpdaifgetmvelgapfslkglmgnpicspqywkpstfggevgfkiintasiqslicnn
vkgcpftsfnvq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1cx2C (C:)
anpccsnpcqnrgecmstgfdqykcdctrtgfygencttpefltriklllkptpntvhyi
lthfkgvwnivnnipflrslimkyvltsrsylidspptynvhygyksweafsnlsyytra
lppvaddcptpmgvkgnkelpdskevlekvllrrefipdpqgsnmmfaffaqhfthqffk
tdhkrgpgftrglghgvdlnhiygetldrqhklrlfkdgklkyqviggevypptvkdtqv
emiypphipenlqfavgqevfglvpglmmyatiwlrehqrvcdilkqehpewgdeqlfqt
skliligetikiviedyvqhlsgyhfklkfdpellfnqqfqyqnriasefntlyhwhpll
pdtfniedqeysfkqflynnsillehgltqfvesftrqiagrvaggrnvpiavqavakas
idqsremkyqslneyrkrfslkpytsfeeltgekemaaelkalysdidvmelypallvek
prpdaifgetmvelgapfslkglmgnpicspqywkpstfggevgfkiintasiqslicnn
vkgcpftsfnvqdpqptktatinasashsrlddinptvlikrrstel

    Sequence, based on observed residues (ATOM records): (download) 
    >1cx2C (C:)
anpccsnpcqnrgecmstgfdqykcdctrtgfygencttpefltriklllkptpntvhyi
lthfkgvwnivnnipflrslimkyvltsrsylidspptynvhygyksweafsnlsyytra
lppvaddcptpmgvkgnkelpdskevlekvllrrefipdpqgsnmmfaffaqhfthqffk
tdhkrgpgftrglghgvdlnhiygetldrqhklrlfkdgklkyqviggevypptvkdtqv
emiypphipenlqfavgqevfglvpglmmyatiwlrehqrvcdilkqehpewgdeqlfqt
skliligetikiviedyvqhlsgyhfklkfdpellfnqqfqyqnriasefntlyhwhpll
pdtfniedqeysfkqflynnsillehgltqfvesftrqiagrvaggrnvpiavqavakas
idqsremkyqslneyrkrfslkpytsfeeltgekemaaelkalysdidvmelypallvek
prpdaifgetmvelgapfslkglmgnpicspqywkpstfggevgfkiintasiqslicnn
vkgcpftsfnvq

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1cx2D (D:)
anpccsnpcqnrgecmstgfdqykcdctrtgfygencttpefltriklllkptpntvhyi
lthfkgvwnivnnipflrslimkyvltsrsylidspptynvhygyksweafsnlsyytra
lppvaddcptpmgvkgnkelpdskevlekvllrrefipdpqgsnmmfaffaqhfthqffk
tdhkrgpgftrglghgvdlnhiygetldrqhklrlfkdgklkyqviggevypptvkdtqv
emiypphipenlqfavgqevfglvpglmmyatiwlrehqrvcdilkqehpewgdeqlfqt
skliligetikiviedyvqhlsgyhfklkfdpellfnqqfqyqnriasefntlyhwhpll
pdtfniedqeysfkqflynnsillehgltqfvesftrqiagrvaggrnvpiavqavakas
idqsremkyqslneyrkrfslkpytsfeeltgekemaaelkalysdidvmelypallvek
prpdaifgetmvelgapfslkglmgnpicspqywkpstfggevgfkiintasiqslicnn
vkgcpftsfnvqdpqptktatinasashsrlddinptvlikrrstel

    Sequence, based on observed residues (ATOM records): (download) 
    >1cx2D (D:)
anpccsnpcqnrgecmstgfdqykcdctrtgfygencttpefltriklllkptpntvhyi
lthfkgvwnivnnipflrslimkyvltsrsylidspptynvhygyksweafsnlsyytra
lppvaddcptpmgvkgnkelpdskevlekvllrrefipdpqgsnmmfaffaqhfthqffk
tdhkrgpgftrglghgvdlnhiygetldrqhklrlfkdgklkyqviggevypptvkdtqv
emiypphipenlqfavgqevfglvpglmmyatiwlrehqrvcdilkqehpewgdeqlfqt
skliligetikiviedyvqhlsgyhfklkfdpellfnqqfqyqnriasefntlyhwhpll
pdtfniedqeysfkqflynnsillehgltqfvesftrqiagrvaggrnvpiavqavakas
idqsremkyqslneyrkrfslkpytsfeeltgekemaaelkalysdidvmelypallvek
prpdaifgetmvelgapfslkglmgnpicspqywkpstfggevgfkiintasiqslicnn
vkgcpftsfnvq