PDB entry 1cwo

View 1cwo on RCSB PDB site
Description: human cyclophilin a complexed with thr2, leu5, d-hiv8, leu10 cyclosporin
Class: isomerase/immunosuppressant
Keywords: isomerase-immunosuppressant complex, cyclophilin-cyclosporin complex, cyclosporin c, immunosuppressant
Deposited on 1998-06-05, released 1998-08-12
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-27, with a file datestamp of 2011-07-22.
Experiment type: XRAY
Resolution: 1.86 Å
R-factor: N/A
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peptidyl-prolyl cis-trans isomerase A
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1cwoa_
  • Chain 'C':
    Compound: cyclosporin c
    Species: Tolypocladium inflatum, synthetic [TaxId:29910]
    Database cross-references and differences (RAF-indexed):
    • NOR NOR00035 (0-10)
      • engineered mutation (0)
      • engineered mutation (2)
      • engineered mutation (8)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1cwoA (A:)

  • Chain 'C':
    No sequence available.